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We provide     implementations of many dose-finding clinical trial designs, including the     continual reassessment method (CRM) by O'Quigley et al. (1990)     <doi:10.2307/2531628>, the toxicity probability interval (TPI) design by Ji    et al. (2007) <doi:10.1177/1740774507079442>, the modified TPI (mTPI) design    by Ji et al. (2010) <doi:10.1177/1740774510382799>, the Bayesian optimal     interval design (BOIN) by Liu & Yuan (2015) <doi:10.1111/rssc.12089>, EffTox    by Thall & Cook (2004) <doi:10.1111/j.0006-341X.2004.00218.x>; the design of    Wages & Tait (2015) <doi:10.1080/10543406.2014.920873>, and the 3+3     described by Korn et al. (1994) <doi:10.1002/sim.4780131802>. All designs    are implemented with a common interface. 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Having provided a flexible interface for specifying designs, we then provide    functions to run simulations and calculate dose-paths for future cohorts of     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