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Specifically, for a space \\(A\\), let \\(C(A)\\) denote the class generated by \\(A\\) using the operations of taking homotopy push-outs and wedges. Then \\(X\\in C(A)\\) is denoted by \\(X>>A\\) (i.e. \\(X\\) is \\(A\\)-cellular) and is referred to as a cellular inequality. Another cellular inequality, \\(X>A\\) (i.e. \\(X\\) is \\(A\\)-acyclic) may also be defined denoting the fact that \\(X\\) is built from \\(A\\) by the operations above as well as by extensions by fibrations. Cellular inequalities were introduced by \\textit{E. Dror Farjoun} [ Cellular spaces, null spaces and homotopy localization, Lect. Notes Math. 1622 (1995; Zbl 0842.55001)] and have found much application. The paper at hand considers the problem of determining when cellular inequalities may be desuspended or delooped. In particular, if \\(\\Sigma X>>\\Sigma A\\), when is it true that \\(X>>A\\) as well? The author gives several equivalent conditions to desuspending a cellular inequality, among which is the interesting condition that \\(\\Sigma X>> \\Sigma A\\) may be desuspended if and only if there exists a connected space \\(B\\) with \\(C(A)=C(\\Omega B)\\). The \\(\\Sigma X>\\Sigma A\\) case and the dual delooping situation are also considered with analogous results. Although the paper centers on the desuspension-delooping problem, it is packed with fundamental techniques and results in this area as well as connections with classical homotopical topics such as Ganea's fibre-cofibre construction, James's construction and a (generalized) Freudenthal suspension 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