{"entities":{"Q1668874":{"pageid":1679615,"ns":120,"title":"Item:Q1668874","lastrevid":68225109,"modified":"2026-04-12T22:15:52Z","type":"item","id":"Q1668874","labels":{"en":{"language":"en","value":"Comparative study of metaheuristics for the curve-fitting problem: modeling neurotransmitter diffusion and synaptic receptor activation"}},"descriptions":{"en":{"language":"en","value":"scientific article; zbMATH DE number 6929050"}},"aliases":{},"claims":{"P31":[{"mainsnak":{"snaktype":"value","property":"P31","hash":"fd5912e4dab4b881a8eb0eb27e7893fef55176ad","datavalue":{"value":{"entity-type":"item","numeric-id":56887,"id":"Q56887"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$8491535F-7978-4594-B2E8-3696A557D367","rank":"normal"}],"P159":[{"mainsnak":{"snaktype":"value","property":"P159","hash":"7deff22676ab9c99ef0fe1725a3a6c78f60a9edb","datavalue":{"value":{"text":"Comparative study of metaheuristics for the curve-fitting problem: modeling neurotransmitter diffusion and synaptic receptor activation","language":"en"},"type":"monolingualtext"},"datatype":"monolingualtext"},"type":"statement","id":"Q1668874$FCDC06F6-A163-4D6A-A02C-CD6B9EEDE677","rank":"normal"}],"P225":[{"mainsnak":{"snaktype":"value","property":"P225","hash":"cb6f0966922c4761b085fb1d9f5d4839c8aa2b8e","datavalue":{"value":"1433.92013","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1668874$2DF19D85-2DF2-46AB-8FC9-A655F882912F","rank":"normal"}],"P27":[{"mainsnak":{"snaktype":"value","property":"P27","hash":"f84093920d82a2245f5fdf2e33d56ebe38b00bd0","datavalue":{"value":"10.1155/2015/708131","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1668874$6A5C3D29-B135-40DE-95E0-86D228DB7129","rank":"normal"}],"P16":[{"mainsnak":{"snaktype":"value","property":"P16","hash":"47d037fcb22286aa4a1731ab40bbbd7abfd0431c","datavalue":{"value":{"entity-type":"item","numeric-id":385453,"id":"Q385453"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$D014879F-66BE-43F4-BC82-0C65C1C4973D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"c0e279235787042e82bb0b6a29469db4d6c1f854","datavalue":{"value":{"entity-type":"item","numeric-id":726141,"id":"Q726141"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$75BE0C23-24E2-4851-8ACF-7AC7A9C06C8A","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"d13f68c14d4e67c7e3265a727f490d21d378a660","datavalue":{"value":{"entity-type":"item","numeric-id":726140,"id":"Q726140"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$1B102D73-8B22-462B-9E6A-82A3A328DAE7","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"6b9b587b339929d6ddcfe3506a522158efcf9363","datavalue":{"value":{"entity-type":"item","numeric-id":1668872,"id":"Q1668872"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$A9CA4247-B42A-4783-BB46-A3F526A2DAB3","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"3103a972c942b14a348b5cc20e3a38285b24322a","datavalue":{"value":{"entity-type":"item","numeric-id":2037486,"id":"Q2037486"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$003A22C8-FED0-42BE-B501-266DAE9643F2","rank":"normal"}],"P200":[{"mainsnak":{"snaktype":"value","property":"P200","hash":"d57614e948fd3618212cc11761c25c64d9f566a6","datavalue":{"value":{"entity-type":"item","numeric-id":162718,"id":"Q162718"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$95E81E36-F58F-49F2-97E1-91F5364F21D1","rank":"normal"}],"P28":[{"mainsnak":{"snaktype":"value","property":"P28","hash":"d467f198e8cd5f81e8828c7ef265401fce8f32ba","datavalue":{"value":{"time":"+2018-08-29T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q1668874$054CB32E-5AB5-428F-82AC-CCC17D49C754","rank":"normal"}],"P1448":[{"mainsnak":{"snaktype":"value","property":"P1448","hash":"1d965e58198fdb57221ba53521664b127bab19c4","datavalue":{"value":"Summary: Synapses are key elements in the information transmission in the nervous system. Among the different approaches to study them, the use of computational simulations is identified as the most promising technique. Simulations, however, do not provide generalized models of the underlying biochemical phenomena, but a set of observations, or time-series curves, displaying the behavior of the synapse in the scenario represented. Finding a general model of these curves, like a set of mathematical equations, could be an achievement in the study of synaptic behavior. In this paper, we propose an exploratory analysis in which selected curve models are proposed, and state-of-the-art metaheuristics are used and compared to fit the free coefficients of these curves to the data obtained from simulations. Experimental results demonstrate that several models can fit these data, though a deeper analysis from a biological perspective reveals that some are better suited for this purpose, as they represent more accurately the biological process. Based on the results of this analysis, we propose a set of mathematical equations and a methodology, adequate for modeling several aspects of biochemical synaptic behavior.","type":"string"},"datatype":"string"},"type":"statement","id":"Q1668874$B6B7BF86-519C-43EA-8EBB-8AAD5D2A19AD","rank":"normal"}],"P226":[{"mainsnak":{"snaktype":"value","property":"P226","hash":"deb6ff57da5c76ad659aeb94b3df9cd98b4ae6e1","datavalue":{"value":"92C37","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1668874$BD7A813B-BB94-42CD-B8EB-3237912A3374","rank":"normal"}],"P1451":[{"mainsnak":{"snaktype":"value","property":"P1451","hash":"cf2b8e04d5d3e49124fc5a62cef364b727cb9361","datavalue":{"value":"6929050","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1668874$98278AD6-4575-420D-AA69-F380C32AE075","rank":"normal"}],"P1463":[{"mainsnak":{"snaktype":"value","property":"P1463","hash":"46e71f4665b8d6fd3049fc94692c44a1efb38b53","datavalue":{"value":{"entity-type":"item","numeric-id":35723,"id":"Q35723"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$4664EE79-BAD3-417A-8D91-266909EA6E1D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1463","hash":"a709ac7c97c67049e241e0b036253f1d955c589a","datavalue":{"value":{"entity-type":"item","numeric-id":13313,"id":"Q13313"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$2DC59715-848B-4E35-AB5B-682489934A62","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1463","hash":"a12114fd83138238072a552976b0d5c033f5922c","datavalue":{"value":{"entity-type":"item","numeric-id":18255,"id":"Q18255"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$D4F6B405-58C0-49A0-9F47-507D33725BC1","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1463","hash":"b2f45492d0a9ee38c7f6f7ea29a7881599069d9b","datavalue":{"value":{"entity-type":"item","numeric-id":13519,"id":"Q13519"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$425B8F70-5E36-4F58-B31D-F9C7E032CBED","rank":"normal"}],"P1460":[{"mainsnak":{"snaktype":"value","property":"P1460","hash":"57f7fea50d2ce1b39b695c4a1313582eed405e38","datavalue":{"value":{"entity-type":"item","numeric-id":5976449,"id":"Q5976449"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$AF23973E-8DBA-4957-BEDA-F1CCD13C4978","rank":"normal"}],"P205":[{"mainsnak":{"snaktype":"value","property":"P205","hash":"21639f3fdc6ae6a975f6472a9f31130793083c19","datavalue":{"value":"https://doi.org/10.1155/2015/708131","type":"string"},"datatype":"url"},"type":"statement","id":"Q1668874$B37B3EF9-B180-410A-B8A7-F12EB2A8797C","rank":"normal"}],"P388":[{"mainsnak":{"snaktype":"value","property":"P388","hash":"c7a11ab4d07c3e010ea0be540ac47ab98543e4af","datavalue":{"value":"W1959261626","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1668874$E0D4B3CD-EFFF-402E-BF20-0347A9F331BD","rank":"normal"}],"P12":[{"mainsnak":{"snaktype":"value","property":"P12","hash":"0a22dacbd6714a4b97d3e7a819067e9eb2947759","datavalue":{"value":"Q59101402","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1668874$D6B41FAB-C699-4EEB-A3E1-12887CCEB9EA","rank":"normal"}],"P223":[{"mainsnak":{"snaktype":"value","property":"P223","hash":"43a0ae3b5263fd3d988ffbaa425f1b6ee8add8f7","datavalue":{"value":{"entity-type":"item","numeric-id":3648613,"id":"Q3648613"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$0F1B59DE-5C83-4E08-A95B-EABE3A5E6183","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"06e0128d2ed6da35bd3ef39033b07f01c5ec36a7","datavalue":{"value":{"entity-type":"item","numeric-id":2655965,"id":"Q2655965"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$36B8AE04-ADA2-47E3-9A89-2A8DB011EA91","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"34660e97bf7d0633c17652108b12ef7c607c0cc0","datavalue":{"value":{"entity-type":"item","numeric-id":4040937,"id":"Q4040937"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$71670C81-1BEF-44CB-8174-6F6990C14FA8","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"08fabf1dafa8be64565b7546373aebc198107ea2","datavalue":{"value":{"entity-type":"item","numeric-id":4695273,"id":"Q4695273"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$00385477-BA03-416E-8446-2E904AFB4636","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"ca02c48bbc5c6c9045bf62ee3dff815f6a3da63d","datavalue":{"value":{"entity-type":"item","numeric-id":4079017,"id":"Q4079017"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$E7C3B6FB-5BC9-4511-89C1-DC8EBB967B41","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"2dfac7a889a27c2e4d3963c387b796bd3cff0966","datavalue":{"value":{"entity-type":"item","numeric-id":1376522,"id":"Q1376522"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$9FECF041-6067-469F-BD3D-A8C01A77DDEF","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"8ce1a0388ca2c08a60d444c1b0d3ea394741b440","datavalue":{"value":{"entity-type":"item","numeric-id":3968769,"id":"Q3968769"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$DD325E5D-7165-42BD-9A89-3D58BB09A131","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"3f52d2e840e32f42df604cb0c1c578efe793b007","datavalue":{"value":{"entity-type":"item","numeric-id":5490902,"id":"Q5490902"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$3AE4AF1B-B733-4911-BB66-30EFE29662F3","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"83ec71e9eeb013d2adb24015465f0b0b799c2093","datavalue":{"value":{"entity-type":"item","numeric-id":3876834,"id":"Q3876834"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$FBD7FE84-ACF6-40DD-AB98-F9A49FAF7CD4","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"6cbd845d677d39a8da7869f473d95a35d2d27879","datavalue":{"value":{"entity-type":"item","numeric-id":1044246,"id":"Q1044246"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$1F5D0406-AECB-4574-8553-1C47A246B315","rank":"normal"}],"P1643":[{"mainsnak":{"snaktype":"value","property":"P1643","hash":"715d5e53b96302da7f67bcfd839e0302c449b61a","datavalue":{"value":{"entity-type":"item","numeric-id":5212888,"id":"Q5212888"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"b1d6e2d234065acd60124866cb5bf7ff911ef9fd","datavalue":{"value":{"amount":"+0.6899252533912659","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1668874$D6562E76-0B6E-4F77-B553-BC298831EAF7","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"dfeca5579302eed8be8bb75680e5c9b007f5979c","datavalue":{"value":{"entity-type":"item","numeric-id":2376474,"id":"Q2376474"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"ca8cc2dfbf00bf9cb28cee11859c7cd3c87ad6ff","datavalue":{"value":{"amount":"+0.6749614477157593","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1668874$B63E12E5-64AC-471D-AA42-11204D68080D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"93bbf85971119f7e4c51f1e04fb349b32df229dc","datavalue":{"value":{"entity-type":"item","numeric-id":5220436,"id":"Q5220436"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"5055a7057220cd60ec3122a681ed174d5d0e26a6","datavalue":{"value":{"amount":"+0.6663286089897156","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1668874$EDF91C03-FE73-4099-A3A0-EE33D6786274","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"feaa8a0b1e6db6f485034cf6bd1e54da9ed6bf86","datavalue":{"value":{"entity-type":"item","numeric-id":2780070,"id":"Q2780070"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"8dc68f8f4cbb6d616c1beaffe99881d0748750f1","datavalue":{"value":{"amount":"+0.6633626818656921","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1668874$03D1813F-2480-4622-A258-A8C25BAB9B0E","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"cec2c26c3a69cbc8678aa587d7ed932e51cba184","datavalue":{"value":{"entity-type":"item","numeric-id":3123361,"id":"Q3123361"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"07021b61739d08f07cb3037285e1bddff17e75f1","datavalue":{"value":{"amount":"+0.6535577774047852","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1668874$99533DCB-9081-40CD-8DB3-13716A0A185B","rank":"normal"}],"P163":[{"mainsnak":{"snaktype":"value","property":"P163","hash":"daf5f856a5d861312ad309ab567540337a5f61d6","datavalue":{"value":{"entity-type":"item","numeric-id":57050,"id":"Q57050"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1668874$B8CCE27C-A100-403E-9667-1B382A2EFBE8","rank":"normal"}]},"sitelinks":{"mardi":{"site":"mardi","title":"Comparative study of metaheuristics for the curve-fitting problem: modeling neurotransmitter diffusion and synaptic receptor activation","badges":[],"url":"https://portal.mardi4nfdi.de/wiki/Comparative_study_of_metaheuristics_for_the_curve-fitting_problem:_modeling_neurotransmitter_diffusion_and_synaptic_receptor_activation"}}}}}