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A large amount of literature on this subject is analysis-based methods. These methods assign various forward measurements of the image. Meanwhile, synthesis-based methods are another well-known class of methods. These methods seek a reconstruction of the image. In this paper, we propose an approach that combines analysis with synthesis methods. The method is proposed to address Poissonian image deconvolution problem by minimizing the energy functional, which is composed of a sparse representation prior over a learned dictionary, the data fidelity term, and framelet based analysis prior constraint as the regularization term. The minimization problem can be efficiently solved by the split Bregman technique. Experiments demonstrate that our approach achieves better results than many state-of-the-art methods, in terms of both restoration accuracy and visual 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