{"entities":{"Q1820076":{"pageid":1830818,"ns":120,"title":"Item:Q1820076","lastrevid":73637733,"modified":"2026-04-14T16:44:59Z","type":"item","id":"Q1820076","labels":{"en":{"language":"en","value":"A stochastic model for the origin and treatment of tumors containing drug-resistant cells"}},"descriptions":{"en":{"language":"en","value":"scientific article; zbMATH DE number 3993349"}},"aliases":{},"claims":{"P31":[{"mainsnak":{"snaktype":"value","property":"P31","hash":"fd5912e4dab4b881a8eb0eb27e7893fef55176ad","datavalue":{"value":{"entity-type":"item","numeric-id":56887,"id":"Q56887"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$37796EA8-3C38-40B4-833A-A893FDB5DE06","rank":"normal"}],"P159":[{"mainsnak":{"snaktype":"value","property":"P159","hash":"f8fa13cce25e166f507c2da7daf9f4978ec68812","datavalue":{"value":{"text":"A stochastic model for the origin and treatment of tumors containing drug-resistant cells","language":"en"},"type":"monolingualtext"},"datatype":"monolingualtext"},"type":"statement","id":"Q1820076$0A71E499-9F0A-46BF-8B7A-042E44212CAC","rank":"normal"}],"P225":[{"mainsnak":{"snaktype":"value","property":"P225","hash":"4120f38162ecff96631e541a2db79200f6e8a08e","datavalue":{"value":"0613.92006","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1820076$42C5F597-989B-4A67-8A42-F3444E8B1F69","rank":"normal"}],"P27":[{"mainsnak":{"snaktype":"value","property":"P27","hash":"26f445a9f0340cdff11596fb5e950e70cd6798a2","datavalue":{"value":"10.1007/BF02459682","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1820076$8151AEF4-86C3-4633-92AD-ED9A5BD49B05","rank":"normal"}],"P200":[{"mainsnak":{"snaktype":"value","property":"P200","hash":"4a6f7d015df5f02e6fe02ce89bcd002530eaade1","datavalue":{"value":{"entity-type":"item","numeric-id":85622,"id":"Q85622"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$7FFDB03F-B483-4195-8353-C184FF371865","rank":"normal"}],"P28":[{"mainsnak":{"snaktype":"value","property":"P28","hash":"63df7153432d81fa42019fcabb076c89649b0b5b","datavalue":{"value":{"time":"+1986-00-00T00:00:00Z","timezone":0,"before":0,"after":0,"precision":9,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q1820076$2F84440D-603F-4978-91FE-A66AE37EB69D","rank":"normal"}],"P1448":[{"mainsnak":{"snaktype":"value","property":"P1448","hash":"7b3078806e23595e7d3cf148da13bece79945cd4","datavalue":{"value":"A stochastic model for the chemotherapy of experimental tumors is presented. The focus of this model is on the presence of drug-resistant mutants and their influence on eventual treatment outcome. Equations are derived for the joint probability-generating function for the number of chemo-sensitive and chemo-resistant cells. The model is extended to two drugs and it is shown how the model may be used to make deductions regarding the optimum scheduling of therapy.","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$B89B5D45-E81A-4472-ABA8-B99252CE3E6A","rank":"normal"}],"P226":[{"mainsnak":{"snaktype":"value","property":"P226","hash":"e27beffea4779e8a96e7c5961e8cc7879483d808","datavalue":{"value":"92C50","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1820076$F9D293A1-FA5F-4471-9F1F-9032EED7B840","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"208daa359f764563c0b4736dfe251df697e9c22d","datavalue":{"value":"60K99","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1820076$0E6B1156-2B2D-4C64-9F2B-E9C032F34F23","rank":"normal"}],"P1451":[{"mainsnak":{"snaktype":"value","property":"P1451","hash":"a8ef9132c5ecbb008be71105214b6d1b7f0eb3ce","datavalue":{"value":"3993349","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1820076$BEE1B520-C785-484F-91D0-CEA3730060A3","rank":"normal"}],"P1450":[{"mainsnak":{"snaktype":"value","property":"P1450","hash":"283da7355df2dba6925a012fbe431de59a5fcd8a","datavalue":{"value":"Kolmogorov forward equations","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$B8AE549B-ACD7-4982-A8B6-5887D4D6900D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"8be066f220e78542ac29d26a77f7b0a1d4870f07","datavalue":{"value":"stochastic model","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$F092C633-3417-48B7-9660-7F9AA2A609ED","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"d856d000e4ecf8e408ca79ad044469fede971c2b","datavalue":{"value":"chemotherapy of experimental tumors","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$D7D6D66A-57DA-4FFD-BF1F-5588E0F8FC38","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"b3daf4ac26090cb2ed1a3828abe7f94524930bea","datavalue":{"value":"drug-resistant mutants","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$97A8B941-9839-4083-BF01-E69956B69D0E","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"4cf64face56879c1fb8644212b0739b2f0d9e8a6","datavalue":{"value":"joint probability-generating function","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$773A57BD-5436-4268-8D51-29F38F514BAF","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"263d4b7b8963024a9ec5d5a311d5243836da18ed","datavalue":{"value":"chemo-sensitive and chemo-resistant cells","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$470B3AD6-E695-48CE-9879-EBA87D9B191C","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"a089df914aeca6807a334630d19b9b2ed86036eb","datavalue":{"value":"optimum scheduling of therapy","type":"string"},"datatype":"string"},"type":"statement","id":"Q1820076$027AEE40-DFD7-45B1-8C40-40D5B10984BF","rank":"normal"}],"P12":[{"mainsnak":{"snaktype":"value","property":"P12","hash":"478b66da482ffff9ae7e7c5ff648296371432cf2","datavalue":{"value":"Q52650549","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q1820076$9858856E-C78C-4AD7-B82C-C51EDC226828","rank":"normal"}],"P16":[{"mainsnak":{"snaktype":"value","property":"P16","hash":"0d3f7f9e1c4398352572b638a8cd521418e82aff","datavalue":{"value":{"entity-type":"item","numeric-id":1064976,"id":"Q1064976"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$262CBE30-724D-45E8-89D6-8BFE83AA5C40","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"0f4ddf528c5725927622a42eaecbc6fbd9a803fc","datavalue":{"value":{"entity-type":"item","numeric-id":1064977,"id":"Q1064977"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$C85A43D6-3516-475E-91E0-A861F87DBFE1","rank":"normal"}],"P1460":[{"mainsnak":{"snaktype":"value","property":"P1460","hash":"57f7fea50d2ce1b39b695c4a1313582eed405e38","datavalue":{"value":{"entity-type":"item","numeric-id":5976449,"id":"Q5976449"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$976A4534-CCAF-4DF6-A710-2F8F31A18A78","rank":"normal"}],"P223":[{"mainsnak":{"snaktype":"value","property":"P223","hash":"f2af213eea0635736842a482d348e31646965f68","datavalue":{"value":{"entity-type":"item","numeric-id":762091,"id":"Q762091"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$2B097DC1-D4D1-46AB-AEE5-9E4896D24626","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"7053ac08311dbedebb474304d4566bc9de324d61","datavalue":{"value":{"entity-type":"item","numeric-id":1055358,"id":"Q1055358"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$A61C34F4-E807-4735-A265-8DD9BB285DD9","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"36496e63784a227663f18027e8c4e6a374ae6c83","datavalue":{"value":{"entity-type":"item","numeric-id":1064978,"id":"Q1064978"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$3F746ADD-9415-4D65-ADBC-EF5789927019","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"2fe9d7268d8ebc747e69e3ab63c3224b2b31743e","datavalue":{"value":{"entity-type":"item","numeric-id":5624492,"id":"Q5624492"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$E3264CCE-DCE5-4162-8B89-20811B909F2A","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"796bae0c8d63ca7f85914836a33fa77055637b6d","datavalue":{"value":{"entity-type":"item","numeric-id":2962146,"id":"Q2962146"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q1820076$41870A1C-817C-479A-8C41-F7C51ADF47E9","rank":"normal"}],"P1643":[{"mainsnak":{"snaktype":"value","property":"P1643","hash":"f11f3eda92f94da0692de7d83ddf015d3aa59495","datavalue":{"value":{"entity-type":"item","numeric-id":1262234,"id":"Q1262234"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"3011257362de25f874d0702aa0ac5295e167c40c","datavalue":{"value":{"amount":"+0.8633344769477844","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1820076$CF32C7FD-0C0A-4836-A3A3-B94384EA726F","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"53744002f0727a73b8a226b734af2511085725c2","datavalue":{"value":{"entity-type":"item","numeric-id":3565679,"id":"Q3565679"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"0b9f630ccc0c72c802b8836c96540d94b3c57e6e","datavalue":{"value":{"amount":"+0.8537412285804749","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1820076$6B83BAE8-4FCF-4E9E-A11A-ED9A07DFC0DB","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"d55c45bd58e4787ec817f5abed0f34e93678bb0f","datavalue":{"value":{"entity-type":"item","numeric-id":751535,"id":"Q751535"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"5bfe1e7fb05d03ae9c84758347bbeddbccbf54bc","datavalue":{"value":{"amount":"+0.8340680003166199","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1820076$FD73B1A6-6319-4036-AB27-3E1789093D39","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"66fbb52f607510624dc026a7638abbbbf8ca5929","datavalue":{"value":{"entity-type":"item","numeric-id":1060984,"id":"Q1060984"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"26b34a3a7c223b0e0611f5406612d66ad218458f","datavalue":{"value":{"amount":"+0.8233987092971802","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1820076$080BAC98-32E1-4861-AEA5-DF1E2AE0CE29","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"085b84fba1c08bde278f9f64db20d3ef98a2f8e0","datavalue":{"value":{"entity-type":"item","numeric-id":3392414,"id":"Q3392414"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"575689a4201d88562c70fb17b908e99067dbf628","datavalue":{"value":{"amount":"+0.81072998046875","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q1820076$F1DF0610-CDDC-4CA1-BBC5-B3D4B5E3A2C0","rank":"normal"}]},"sitelinks":{"mardi":{"site":"mardi","title":"A stochastic model for the origin and treatment of tumors containing drug-resistant cells","badges":[],"url":"https://portal.mardi4nfdi.de/wiki/A_stochastic_model_for_the_origin_and_treatment_of_tumors_containing_drug-resistant_cells"}}}}}