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Clustered and recurrent survival times can    be studied.  2) Additive frailty models for proportional hazard models    with two correlated random effects (intercept random effect with    random slope).  3) Nested frailty models for hierarchically clustered    data (with 2 levels of clustering) by including two iid gamma random    effects.  4) Joint frailty models in the context of the joint    modelling for recurrent events with terminal event for clustered data    or not. A joint frailty model for two semi-competing risks and    clustered data is also proposed.  5) Joint general frailty models in    the context of the joint modelling for recurrent events with terminal    event data with two independent frailty terms.  6) Joint Nested    frailty models in the context of the joint modelling for recurrent    events with terminal event, for hierarchically clustered data (with    two levels of clustering) by including two iid gamma random effects.    7) Multivariate joint frailty models for two types of recurrent events    and a terminal event.  8) Joint models for longitudinal data and a    terminal event.  9) Trivariate joint models for longitudinal data,    recurrent events and a terminal event.  10) Joint frailty models for    the validation of surrogate endpoints in multiple randomized clinical    trials with failure-time and/or longitudinal endpoints with the    possibility to use a mediation analysis model.  11) Conditional and    Marginal two-part joint models for longitudinal semicontinuous data    and a terminal event.  12) Joint frailty-copula models for the    validation of surrogate endpoints in multiple randomized clinical    trials with failure-time endpoints.  13) Generalized shared and joint    frailty models for recurrent and terminal events. Proportional hazards    (PH), additive hazard (AH), proportional odds (PO) and probit models    are available in a fully parametric framework. For PH and AH models,    it is possible to consider type-varying coefficients and flexible    semiparametric hazard function.  Prediction values are available (for    a terminal event or for a new recurrent event). Left-truncated (not    for Joint model), right-censored data, interval-censored data (only    for Cox proportional hazard and shared frailty model) and strata are    allowed. In each model, the random effects have the gamma or normal    distribution. Now, you can also consider time-varying covariates    effects in Cox, shared and joint frailty models (1-5). The package    includes concordance measures for Cox proportional hazards models and    for shared frailty models.  14) Competing Joint Frailty Model: A    single type of recurrent event and two terminal events.  15) functions     to compute power and sample size for four Gamma-frailty-based designs:     Shared Frailty Models, Nested Frailty Models, Joint Frailty Models, and     General Joint Frailty Models. Each design includes two primary functions: a     power function, which computes power given a specified sample size;     and a sample size function, which computes the required sample size to achieve     a specified power. 16) Weibull Illness-Death model with or without shared frailty    between transitions. Left-truncated and right-censored data are allowed.     17) Weibull Competing risks model with or without shared frailty between the     transitions. Left-truncated and right-censored data are allowed. 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