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Often a treatment applied in a given period has in addition to its direct effect a so-called carryover effect, i.e. it may effect the measurement in the next period. Most papers on optimal crossover designs consider an estimate which is corrected for carryover effects. However, this corrected estimate has a large variance. In this paper the authors consider another way. They use the uncorrected estimate which has a smaller variance but which is biased if carryover effects cannot be neglected. They find crossover designs which are optimal in the sense that they minimize the mean squared error (MSE), i.e. the sum of variance and bias. 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