{"entities":{"Q2013966":{"pageid":2024708,"ns":120,"title":"Item:Q2013966","lastrevid":57351249,"modified":"2026-03-30T14:53:05Z","type":"item","id":"Q2013966","labels":{"en":{"language":"en","value":"Determining cutoff point of ensemble trees based on sample size in predicting clinical dose with DNA microarray data"}},"descriptions":{"en":{"language":"en","value":"scientific article; zbMATH DE number 6759168"}},"aliases":{},"claims":{"P31":[{"mainsnak":{"snaktype":"value","property":"P31","hash":"fd5912e4dab4b881a8eb0eb27e7893fef55176ad","datavalue":{"value":{"entity-type":"item","numeric-id":56887,"id":"Q56887"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$755D81E2-BAAB-44BE-88DF-3C2530EAF617","rank":"normal"}],"P159":[{"mainsnak":{"snaktype":"value","property":"P159","hash":"700c081612858aad01f9c766752ec70365d1413a","datavalue":{"value":{"text":"Determining cutoff point of ensemble trees based on sample size in predicting clinical dose with DNA microarray data","language":"en"},"type":"monolingualtext"},"datatype":"monolingualtext"},"type":"statement","id":"Q2013966$4A162601-1C82-4E55-BC33-53C1A67F7F9B","rank":"normal"}],"P225":[{"mainsnak":{"snaktype":"value","property":"P225","hash":"462e2dacd66093698700dc41069267da68b99195","datavalue":{"value":"1423.92130","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$50F6DBBC-886F-469C-ABA6-3A3B0BE22B5E","rank":"normal"}],"P27":[{"mainsnak":{"snaktype":"value","property":"P27","hash":"2433c11a4d139ec6df93eaf0f81738d1d72539c8","datavalue":{"value":"10.1155/2016/6794916","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$611BF14A-018C-47FF-B9C7-62BAF148C353","rank":"normal"}],"P16":[{"mainsnak":{"snaktype":"value","property":"P16","hash":"2f4e1293118af66690efb8cf846a274cd2ae8487","datavalue":{"value":{"entity-type":"item","numeric-id":2013963,"id":"Q2013963"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$3F9911FE-8628-42B1-8BA4-C494C1E61B8F","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"c38074756d77d6cd5e69567993c310ebe62b90e1","datavalue":{"value":{"entity-type":"item","numeric-id":2013964,"id":"Q2013964"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$58EBBC4B-31AD-4AB9-969C-41EB676484B3","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"8db468e3866981617fb136e5aadf8693406f102d","datavalue":{"value":{"entity-type":"item","numeric-id":2013965,"id":"Q2013965"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$5FF86E03-0D9B-47C0-9506-C7337877E870","rank":"normal"}],"P200":[{"mainsnak":{"snaktype":"value","property":"P200","hash":"ae2a137607979ebaa11579b7aa87d8ebbaf2710b","datavalue":{"value":{"entity-type":"item","numeric-id":278087,"id":"Q278087"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$9BB0009A-035A-406C-AA5A-8CE361182346","rank":"normal"}],"P28":[{"mainsnak":{"snaktype":"value","property":"P28","hash":"6c037d29acd827bf6fcdad2bc0363160e7bcea4e","datavalue":{"value":{"time":"+2017-08-10T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q2013966$3CC2C0A9-8F1D-4F09-AD35-0AD1DE1FDF90","rank":"normal"}],"P1448":[{"mainsnak":{"snaktype":"value","property":"P1448","hash":"eeeebead19bb1f65a1eb2d98c86f2a83173c6e68","datavalue":{"value":"Summary: \\textit{Background/Aim}. Evaluating the success of dose prediction based on genetic or clinical data has substantially advanced recently. The aim of this study is to predict various clinical dose values from DNA gene expression datasets using data mining techniques. \\textit{Materials and Methods}. Eleven real gene expression datasets containing dose values were included. First, important genes for dose prediction were selected using iterative sure independence screening. Then, the performances of regression trees (RTs), support vector regression (SVR), RT bagging, SVR bagging, and RT boosting were examined. \\textit{Results}. The results demonstrated that a regression-based feature selection method substantially reduced the number of irrelevant genes from raw datasets. Overall, the best prediction performance in nine of 11 datasets was achieved using SVR; the second most accurate performance was provided using a gradient-boosting machine (GBM). \\textit{Conclusion}. Analysis of various dose values based on microarray gene expression data identified common genes found in our study and the referenced studies. According to our findings, SVR and GBM can be good predictors of dose-gene datasets. Another result of the study was to identify the sample size of \\(n = 25\\) as a cutoff point for RT bagging to outperform a single RT.","type":"string"},"datatype":"string"},"type":"statement","id":"Q2013966$0A102AD7-63A4-4DC4-BE13-21879068CF2C","rank":"normal"}],"P226":[{"mainsnak":{"snaktype":"value","property":"P226","hash":"e27beffea4779e8a96e7c5961e8cc7879483d808","datavalue":{"value":"92C50","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$9A8DAEE9-9CC2-4E81-8828-692081F91A88","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"708a6f1a75f978962215fcdf6748c16c77f4fd6e","datavalue":{"value":"62P10","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$48B01382-06B4-459A-948E-D5C49A70313F","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"cfe779e91fe9c53ee133568259955801965765ae","datavalue":{"value":"68T05","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$0A66E8B6-9F36-48D2-A319-BE8B123B9486","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"dd617f9d0fec58a219ee24586cc73ce6577bed23","datavalue":{"value":"65C60","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$A7C48E27-E5E7-4370-AD58-9614591674D0","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"5823d607a543702da84952b8d59bfb2f0bb4edc6","datavalue":{"value":"62J05","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$E7E5262B-998D-4438-9322-116265A3480C","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"8a784276b4e09d379c8147965411b455c3d79751","datavalue":{"value":"68T10","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$7CA9C6B0-1B75-4447-9F40-CF6D6E95E285","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"924468f6877a529717a68c43d862e844a6c1f682","datavalue":{"value":"62J12","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$B79D7BC1-287D-43A1-B558-60BCF90FE1BA","rank":"normal"}],"P1451":[{"mainsnak":{"snaktype":"value","property":"P1451","hash":"427e99b7c391e488972154dde83fca0492a70581","datavalue":{"value":"6759168","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$E94C9836-5B9C-4083-B3CD-C7D03BA2DC5B","rank":"normal"}],"P1450":[{"mainsnak":{"snaktype":"value","property":"P1450","hash":"450e6d055e41f8e3bf5d68ddd531bbc66afccc8d","datavalue":{"value":"DNA gene expression microarray data","type":"string"},"datatype":"string"},"type":"statement","id":"Q2013966$C228BBDE-3289-424A-992E-2FFD58671E7D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"8cfb7a60da8859b23f42ebff48b20e8de4acef5d","datavalue":{"value":"clinical dose prediction","type":"string"},"datatype":"string"},"type":"statement","id":"Q2013966$4522DF1A-7941-47FB-8AF8-2EE249337928","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"e1b0983c300f3e3dd98ed2a638bcc83046c1b321","datavalue":{"value":"ensemble trees","type":"string"},"datatype":"string"},"type":"statement","id":"Q2013966$DF935CDB-E3C7-464A-9353-C4E9986E710F","rank":"normal"}],"P12":[{"mainsnak":{"snaktype":"value","property":"P12","hash":"8fcf9917e876c7e4da76631020bd15d805c98b35","datavalue":{"value":"Q31155158","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$7644111E-BCF6-41CB-A820-B99AEDC50587","rank":"normal"}],"P1463":[{"mainsnak":{"snaktype":"value","property":"P1463","hash":"ffc53d83ee7e5cf600a6539883adf149785b90fa","datavalue":{"value":{"entity-type":"item","numeric-id":20009,"id":"Q20009"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$A649FF0A-B332-4BCF-A32F-8D156E49B55D","rank":"normal"}],"P1460":[{"mainsnak":{"snaktype":"value","property":"P1460","hash":"57f7fea50d2ce1b39b695c4a1313582eed405e38","datavalue":{"value":{"entity-type":"item","numeric-id":5976449,"id":"Q5976449"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$F1BDCA60-AED5-4F1B-85D1-A8A087F8E179","rank":"normal"}],"P205":[{"mainsnak":{"snaktype":"value","property":"P205","hash":"2b858cf660d1f03244fbf665957d78dd70fd1130","datavalue":{"value":"https://doi.org/10.1155/2016/6794916","type":"string"},"datatype":"url"},"type":"statement","id":"Q2013966$29F08CE8-D973-4655-BFF0-1106A899D3F1","rank":"normal"}],"P388":[{"mainsnak":{"snaktype":"value","property":"P388","hash":"44359449a0e76998472da9e21e181933c8d36a39","datavalue":{"value":"W2563714500","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2013966$60A297C7-F764-451F-A24D-C93E3B4FF0FD","rank":"normal"}],"P223":[{"mainsnak":{"snaktype":"value","property":"P223","hash":"c3ac0adf24072b4241577ba1b975e6c97e27df09","datavalue":{"value":{"entity-type":"item","numeric-id":733150,"id":"Q733150"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$2D04E383-681B-4FE0-9F82-C4DE70E462F8","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"892596751cb2b62242b0d47116a325905b43fd8c","datavalue":{"value":{"entity-type":"item","numeric-id":4632602,"id":"Q4632602"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$5BE0F8A9-0C1F-4616-9AB4-95E0D3213571","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"b3a53d24f4b7d15ab9cefa78c0b997ec28a55cf5","datavalue":{"value":{"entity-type":"item","numeric-id":5943421,"id":"Q5943421"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$72BE4E0B-E7C9-41DD-8E24-7FDEB6ECCCC7","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"1a08a2389192c4a9237b64c1e9662bba3d75a5ba","datavalue":{"value":{"entity-type":"item","numeric-id":65108,"id":"Q65108"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$C09FC2EE-879C-47A3-9062-23D4714DB2CD","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"a46dedcc016fa1c5054ce08b2d644f9d110b7556","datavalue":{"value":{"entity-type":"item","numeric-id":449780,"id":"Q449780"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$00C0760D-59F9-4C21-BF4C-9DC077850AF2","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"5726fd106697b2a1b6af1f2ba8d50d34ea469b5f","datavalue":{"value":{"entity-type":"item","numeric-id":5959948,"id":"Q5959948"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$08F5B40F-52C8-4BA7-8CC0-1EAC31EE5994","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"c00b6f34b0b96748031bd21a50ae6f0a150d31b7","datavalue":{"value":{"entity-type":"item","numeric-id":5958470,"id":"Q5958470"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$DFA692A2-E6CD-449A-A1F3-8844FE36D07F","rank":"normal"}],"P1643":[{"mainsnak":{"snaktype":"value","property":"P1643","hash":"b5ffb540840c09ec9c0801a1756578babd24e599","datavalue":{"value":{"entity-type":"item","numeric-id":961312,"id":"Q961312"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"247e9e9a9edda27fadc221a8349eaa81e0139cce","datavalue":{"value":{"amount":"+0.6489140391349792","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2013966$57CE20D3-5239-446D-9C8F-0F0B7F96FC69","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"301cadb13a4cea305b7fb66c42e9ae2d310947ef","datavalue":{"value":{"entity-type":"item","numeric-id":1023556,"id":"Q1023556"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"89b4a5163bc7a33135f498ce72d8f63d14f1c467","datavalue":{"value":{"amount":"+0.6435614824295044","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2013966$5338A654-7FB6-45F1-8E9C-30F0202EFF31","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"7cd9214c40c42134fd17fd8a3cff5acb46ddd256","datavalue":{"value":{"entity-type":"item","numeric-id":66058,"id":"Q66058"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"3890e5fce52e3669ca710e54760c717df1898a94","datavalue":{"value":{"amount":"+0.6361179947853088","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2013966$CC4098B9-3A0D-4E3D-88DE-B25142B541AB","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"698229af15cf4cd013c8154c120e4770f16ece3b","datavalue":{"value":{"entity-type":"item","numeric-id":5856815,"id":"Q5856815"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"0e85080f6142bbd5bad97d0cdd6da95b4913fac3","datavalue":{"value":{"amount":"+0.6327720880508423","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2013966$EEC232A7-928A-4B0A-BDC8-DAD33F5A45C6","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"8f554a049912a8ca15c0cb0709e732cf73e38fa1","datavalue":{"value":{"entity-type":"item","numeric-id":1402254,"id":"Q1402254"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"efe1fb879463fb9902aa789e18f92f7fb5724633","datavalue":{"value":{"amount":"+0.6275915503501892","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2013966$7A94B091-58C9-46B5-A07F-518007058D1C","rank":"normal"}],"P163":[{"mainsnak":{"snaktype":"value","property":"P163","hash":"45fcd4163b5f33e6e8c784f5522d7246c0a1a61e","datavalue":{"value":{"entity-type":"item","numeric-id":57056,"id":"Q57056"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2013966$ADAFB7C5-65DC-40C3-AEB9-BC815D033ADB","rank":"normal"}]},"sitelinks":{"mardi":{"site":"mardi","title":"Publication:2013966","badges":[],"url":"https://portal.mardi4nfdi.de/wiki/Publication:2013966"}}}}}