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The Dirac operator with infinite mass boundary conditions in \\(L^2(\\Omega,{\\mathbb C}^2)\\) is defined as \\[D^\\Omega := \\begin{pmatrix} 0 & -2\\mathrm{i}\\partial_z\\\\ -2\\mathrm{i}\\partial_{\\bar z} & 0 \\end{pmatrix}, \\] with domain \\(\\{ u = (u_1,u_2)^\\top \\in H^1(\\Omega,{\\mathbb C}^2) : u_2 = \\mathrm{i} \\mathbf{n}u_1 \\text{ on }\\partial\\Omega \\},\\) where \\(\\mathbf{n} := n_1 + \\mathrm{i} n_2\\) and \\(\\partial_z, \\partial_{\\bar{z}}\\) are the Wirtinger operators. The spectrum of \\(D^\\Omega\\) is symmetric with respect to the origin and constituted of eigenvalues of finite multiplicity \\[ \\cdots \\leq -E_k(\\Omega) \\leq\\cdots \\leq-E_{1}(\\Omega) < 0 < E_{1}(\\Omega) \\leq \\cdots \\leq E_k(\\Omega) \\leq \\cdots.\\] The authors prove the following estimate \\[E_1(\\Omega) \\leq \\frac{|\\partial\\Omega|}{(\\pi r_i^2 + |\\Omega|)}E_1({\\mathbb D}) \\] with equality if and only if \\(\\Omega\\) is a disk, where \\(r_i\\) is the inradius of \\(\\Omega\\) and \\(\\mathbb D\\) is the unit disk. \\par The second main result of this paper is the following non-linear variational characterization of \\(E_1(\\Omega)\\). \\(E > 0\\) is the first non-negative eigenvalue of \\(D^\\Omega\\) if and only if \\(\\mu^\\Omega(E) = 0\\), where \\[\\mu^\\Omega(E) := \\inf\\limits_{u} \\frac{4 \\int_\\Omega |\\partial_{\\bar z} u|^2 dx - E^2 \\int_{\\Omega}|u|^2dx + E \\int_{\\partial\\Omega} |u|^2 ds}{\\int_\\Omega |u|^2 dx}.\\] \\par The authors propose the following conjecture \\[\\mu^\\Omega(E) \\geq \\frac{\\pi}{|\\Omega|}\\mu^{\\mathbb D}\\Big(\\sqrt{\\frac{|\\Omega|}{\\pi}}E\\Big), \\forall E>0\\] and provide numerical evidences supporting it. 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