{"entities":{"Q2851584":{"pageid":2862304,"ns":120,"title":"Item:Q2851584","lastrevid":83521268,"modified":"2026-05-07T08:36:45Z","type":"item","id":"Q2851584","labels":{"en":{"language":"en","value":"Adaptive clinical trial designs to detect interaction between treatment and a dichotomous biomarker"}},"descriptions":{"en":{"language":"en","value":"scientific article; zbMATH DE number 6215407"}},"aliases":{},"claims":{"P31":[{"mainsnak":{"snaktype":"value","property":"P31","hash":"fd5912e4dab4b881a8eb0eb27e7893fef55176ad","datavalue":{"value":{"entity-type":"item","numeric-id":56887,"id":"Q56887"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$4DF114E2-9896-442C-96C6-588B03620556","rank":"normal"}],"P159":[{"mainsnak":{"snaktype":"value","property":"P159","hash":"80cdb38d4275ff170d97362fb4735f91ba488ed3","datavalue":{"value":{"text":"Adaptive clinical trial designs to detect interaction between treatment and a dichotomous biomarker","language":"en"},"type":"monolingualtext"},"datatype":"monolingualtext"},"type":"statement","id":"Q2851584$0418C477-A5E3-446D-BF8E-63992ED53167","rank":"normal"}],"P225":[{"mainsnak":{"snaktype":"value","property":"P225","hash":"4da925cc5567d7cd9611b0a06ccdb845790f34f1","datavalue":{"value":"1273.62256","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$7BA96F90-A502-4C0E-93C2-0B0EA9E54745","rank":"normal"}],"P16":[{"mainsnak":{"snaktype":"value","property":"P16","hash":"212e0c9e6f33e0c24977865513a4deaed06a0427","datavalue":{"value":{"entity-type":"item","numeric-id":988003,"id":"Q988003"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$B5FB5440-9DE8-43F0-9D35-3F5B16C37AB2","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"7302658b47dbda30b4ae8c8abc19c19efe1d4281","datavalue":{"value":{"entity-type":"item","numeric-id":221075,"id":"Q221075"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$A6363C54-F6B3-43CA-8FA0-C4B75A1E8068","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"ee393282749bfc3055802fbc5ec0e299f232a16a","datavalue":{"value":{"entity-type":"item","numeric-id":1432859,"id":"Q1432859"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$DF630D9E-AA02-49C8-B24D-9B1F538ED548","rank":"normal"}],"P28":[{"mainsnak":{"snaktype":"value","property":"P28","hash":"26da62d029dc968b405f953bc0f065ae00a7c91b","datavalue":{"value":{"time":"+2013-10-11T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q2851584$73B557A7-D9BD-4971-9F22-F500F2AEE967","rank":"normal"}],"P226":[{"mainsnak":{"snaktype":"value","property":"P226","hash":"708a6f1a75f978962215fcdf6748c16c77f4fd6e","datavalue":{"value":"62P10","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$60F7A6CF-5805-462D-9B82-D5CD7FF337C2","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"e27beffea4779e8a96e7c5961e8cc7879483d808","datavalue":{"value":"92C50","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$CE404E88-500D-41E8-858B-FCF78C48E476","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"dd617f9d0fec58a219ee24586cc73ce6577bed23","datavalue":{"value":"65C60","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$E372AFB1-8E56-410D-BB88-500A203DA7B6","rank":"normal"}],"P1451":[{"mainsnak":{"snaktype":"value","property":"P1451","hash":"07727aa805915742fd96701968d8e28423184d19","datavalue":{"value":"6215407","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$1D0BACAD-B42D-4FE0-B088-D5E00A3A4A03","rank":"normal"}],"P1450":[{"mainsnak":{"snaktype":"value","property":"P1450","hash":"9409c4a85a96a58f224e4e8d924ae95f4615cf71","datavalue":{"value":"adaptive designs","type":"string"},"datatype":"string"},"type":"statement","id":"Q2851584$B0E69EA4-A535-458D-B4CF-47B92D528B20","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"9336d4f06eddee6bed3c5a6e90b6f55534240d0e","datavalue":{"value":"personalized medicine","type":"string"},"datatype":"string"},"type":"statement","id":"Q2851584$8F5102C8-06B5-412A-AEEE-4793C386A5FB","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"cbe0ff6f2c2ded3becccda3386525a2ab1c93d20","datavalue":{"value":"power","type":"string"},"datatype":"string"},"type":"statement","id":"Q2851584$B99CAD9E-3219-4D00-8E1B-5D254AA2145B","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"e11567ab13c4e9ae0101808cea542a80ab8addab","datavalue":{"value":"treatment-biomarker interactions","type":"string"},"datatype":"string"},"type":"statement","id":"Q2851584$4677E57B-440A-45C7-8391-65A76057ED95","rank":"normal"}],"P1460":[{"mainsnak":{"snaktype":"value","property":"P1460","hash":"57f7fea50d2ce1b39b695c4a1313582eed405e38","datavalue":{"value":{"entity-type":"item","numeric-id":5976449,"id":"Q5976449"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$9A5EEF29-40F4-421B-BA75-20CCFDEE868A","rank":"normal"}],"P205":[{"mainsnak":{"snaktype":"value","property":"P205","hash":"467e28baad46c267575078176349f7d0a45e3b95","datavalue":{"value":"https://doi.org/10.1002/cjs.11184","type":"string"},"datatype":"url"},"type":"statement","id":"Q2851584$888E0ABE-55DD-4D0E-9C55-DDFB4302ED13","rank":"normal"}],"P388":[{"mainsnak":{"snaktype":"value","property":"P388","hash":"53422e1550d4f97977fcdeab97f71a4368c3f368","datavalue":{"value":"W1591775948","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$DADC07B0-DD94-4DD7-8F7E-38C6C18ABB16","rank":"normal"}],"P223":[{"mainsnak":{"snaktype":"value","property":"P223","hash":"d05b48c3041c1748b9edb8a4eb4d4dca8154899b","datavalue":{"value":{"entity-type":"item","numeric-id":3942253,"id":"Q3942253"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$B461B1E8-FA9C-4E14-8CD2-F9D9D761510D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"9bb7ff6780cf20f674f02b6b714fdec9699e94e9","datavalue":{"value":{"entity-type":"item","numeric-id":2775636,"id":"Q2775636"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$7D64E108-BABA-44EA-BC05-904B513A2443","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"fe429f24d951c11cc2ee0454e5336e7dc0540f00","datavalue":{"value":{"entity-type":"item","numeric-id":5633522,"id":"Q5633522"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$2278562B-8FE2-46BF-987C-0D1B3D178509","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"e7bd7a9490568e29e85f69d6059e89ee1b75bb14","datavalue":{"value":{"entity-type":"item","numeric-id":5490901,"id":"Q5490901"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$18A1FAC1-FA04-4F20-9D41-DFB70E9D0607","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"89de0dfc1821404634d7b69f08af02d280f76610","datavalue":{"value":{"entity-type":"item","numeric-id":1880900,"id":"Q1880900"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$D27A218A-4A16-4C90-93C4-35077B9B5DF6","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"c6d4826ddd54b59357a9838e41c51dccac6c085e","datavalue":{"value":{"entity-type":"item","numeric-id":3626376,"id":"Q3626376"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$4300AB74-0FB7-4BF4-840C-D74FF16E6936","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"ab6c6f1b66d76abaeb8d81a138350f3426f60307","datavalue":{"value":{"entity-type":"item","numeric-id":834350,"id":"Q834350"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$89111336-5272-4BB9-920E-D88BC55AB31F","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"f8e055d9c0524d6165933645146b11201df11bfe","datavalue":{"value":{"entity-type":"item","numeric-id":693747,"id":"Q693747"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$02E4E27C-5C3A-4A0B-8D04-CFC150D7AE21","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"d9760152e7ee84c953b59e50cc315c5af6ef0dd8","datavalue":{"value":{"entity-type":"item","numeric-id":973877,"id":"Q973877"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$44294373-B508-4102-A76E-C8CDD36C374E","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"31033c6c9f3d05c29bf682bf97c61182aefed180","datavalue":{"value":{"entity-type":"item","numeric-id":4757976,"id":"Q4757976"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$90EA0B7D-3804-411B-87C2-3D6347B4C459","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"6e4a1575a9d43845ef2d26cc21e89cd032aaacbf","datavalue":{"value":{"entity-type":"item","numeric-id":908152,"id":"Q908152"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$4F9A761C-83C6-491E-B87D-BD73ACB5AB40","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"3591c7005812ad48b726fecc07ab94b4f438e5cd","datavalue":{"value":{"entity-type":"item","numeric-id":4171470,"id":"Q4171470"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$F43B1BBB-F910-4CC1-A680-83E8EB663BE8","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"c4da557121186113752fa558990e732776d649e7","datavalue":{"value":{"entity-type":"item","numeric-id":1244960,"id":"Q1244960"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$0CC367EE-084E-4518-A995-1D1C999BD28A","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"3fb4c6e89340c8f858be4cfcbfef5df98d5d157b","datavalue":{"value":{"entity-type":"item","numeric-id":5434029,"id":"Q5434029"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$24A2C5F5-C453-47DF-A6E9-B673222E6C07","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P223","hash":"c20fb65a9eb471b92b6e2c1ce7580876e0d8eaf9","datavalue":{"value":{"entity-type":"item","numeric-id":2642745,"id":"Q2642745"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$4F6A3243-B035-4767-9E99-0741869EF98D","rank":"normal"}],"P27":[{"mainsnak":{"snaktype":"value","property":"P27","hash":"50bcc307fa9d4684f34eddaeeb19e51f26586761","datavalue":{"value":"10.1002/CJS.11184","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q2851584$DEF7B8B4-8E2A-44FF-BE35-DCCDBA312440","rank":"normal"}],"P200":[{"mainsnak":{"snaktype":"value","property":"P200","hash":"5f23c6e926f93587fdc6f7d236bfefe81d713d09","datavalue":{"value":{"entity-type":"item","numeric-id":6490383,"id":"Q6490383"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q2851584$61B2C7F2-FFFC-4005-AC38-97555112BF0E","rank":"normal"}],"P1643":[{"mainsnak":{"snaktype":"value","property":"P1643","hash":"f40c50229923a9c625e55249b5df2931dcec5ba8","datavalue":{"value":{"entity-type":"item","numeric-id":5739265,"id":"Q5739265"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"c7d193e2cb118d64dd672520954f956fd9130839","datavalue":{"value":{"amount":"+0.814725399017334","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2851584$13EE246F-2152-47AF-A398-50B1782FF58D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"1f99b71d63ae99ae4f6bcd49aee2d8adc27bc432","datavalue":{"value":{"entity-type":"item","numeric-id":2800202,"id":"Q2800202"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"7dfd7c951dfd1b51f2dc0260aaee40414fcd8173","datavalue":{"value":{"amount":"+0.7783977389335632","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2851584$B9BC4689-A044-4E2C-A647-354C070F14C4","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"4a70df4bbd0a0b31a32726a7053e0a54d1a4850c","datavalue":{"value":{"entity-type":"item","numeric-id":5128841,"id":"Q5128841"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"ae121ca6709b7d7c95e2cfe3e2f0988829e4098d","datavalue":{"value":{"amount":"+0.7436012625694275","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2851584$D257300F-FD11-4F8A-A032-A7AC6C8E41F2","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"fb8d75fa70937a7e87ce895b5dfee84e9780ad6f","datavalue":{"value":{"entity-type":"item","numeric-id":5138112,"id":"Q5138112"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"8f6db526dff61265c7f89d3d6ecda6d513c2ddae","datavalue":{"value":{"amount":"+0.7350471615791321","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2851584$2243C863-5041-4AFD-88D5-678BCAE18634","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"c95e91806e4cda3f7761268239e0db8bae81b8da","datavalue":{"value":{"entity-type":"item","numeric-id":6079625,"id":"Q6079625"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"45a360f42f15c028b87ca9cd9d92cb49fa309555","datavalue":{"value":{"amount":"+0.7331626415252686","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q2851584$D678D735-6A6A-49BC-B9EA-014F8AE4A139","rank":"normal"}]},"sitelinks":{"mardi":{"site":"mardi","title":"Adaptive clinical trial designs to detect interaction between treatment and a dichotomous biomarker","badges":[],"url":"https://portal.mardi4nfdi.de/wiki/Adaptive_clinical_trial_designs_to_detect_interaction_between_treatment_and_a_dichotomous_biomarker"}}}}}