{"entities":{"Q4260874":{"pageid":6290475,"ns":120,"title":"Item:Q4260874","lastrevid":108484088,"modified":"2026-11-06T16:13:24Z","type":"item","id":"Q4260874","labels":{},"descriptions":{"en":{"language":"en","value":"scientific article; zbMATH DE number 1330292"}},"aliases":{},"claims":{"P31":[{"mainsnak":{"snaktype":"value","property":"P31","hash":"fd5912e4dab4b881a8eb0eb27e7893fef55176ad","datavalue":{"value":{"entity-type":"item","numeric-id":56887,"id":"Q56887"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q4260874$BAF29EE9-EAAA-4A2C-AF71-73A496557A46","rank":"normal"}],"P225":[{"mainsnak":{"snaktype":"value","property":"P225","hash":"b3a8bdb8f6c1137910e5d2a04ac40e8adb594d95","datavalue":{"value":"0927.92015","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q4260874$1430899E-796B-4AD2-BC4C-B489430416BE","rank":"normal"}],"P16":[{"mainsnak":{"snaktype":"value","property":"P16","hash":"87da1c1520b1ab8fb5bcd21db006f58c52267a26","datavalue":{"value":{"entity-type":"item","numeric-id":807496,"id":"Q807496"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q4260874$2E6061CD-8D81-451E-86B6-8C1B52CFDA26","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"1879ccbbbcd75f4e7a87dcd1a7420899a888e783","datavalue":{"value":{"entity-type":"item","numeric-id":4260871,"id":"Q4260871"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q4260874$3D300CAD-2EC0-4F0D-A401-18E2F3E31E42","rank":"normal"}],"P28":[{"mainsnak":{"snaktype":"value","property":"P28","hash":"fb9b4aa9d0b203b9e99aed58aa82b9d85ad6a7f8","datavalue":{"value":{"time":"+1999-12-12T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q4260874$00234FFD-DF5B-4BD9-9479-4EAF18AF61D7","rank":"normal"}],"P226":[{"mainsnak":{"snaktype":"value","property":"P226","hash":"deb6ff57da5c76ad659aeb94b3df9cd98b4ae6e1","datavalue":{"value":"92C37","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q4260874$10D05DE7-8D90-4C3F-8488-29D292E9F94B","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"1cc6a2d1a81aec0cb5abdfe44055f934ac25329b","datavalue":{"value":"92C40","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q4260874$55420243-E910-4027-9A74-A259E3903456","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P226","hash":"78962259eea64bad92910a7ae94b5c7e48391041","datavalue":{"value":"35Q92","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q4260874$C103D8EB-6F50-4775-A434-E5FE442C4CD6","rank":"normal"}],"P1451":[{"mainsnak":{"snaktype":"value","property":"P1451","hash":"c0da41edd9b4439929a64f7dac72e56e1c09a286","datavalue":{"value":"1330292","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q4260874$6E883A17-4BE9-4B96-A322-C6498D29BE76","rank":"normal"}],"P1450":[{"mainsnak":{"snaktype":"value","property":"P1450","hash":"a68ee99cb8bd81eb67e8125689db8e5da1495a48","datavalue":{"value":"diffusion equations","type":"string"},"datatype":"string"},"type":"statement","id":"Q4260874$7238EEBB-9C4F-4DD4-8993-E37959F1F590","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"2d45e4286e33a8e52f4c871a0153f39f81c6b0d1","datavalue":{"value":"receptor-mediated endocytosis","type":"string"},"datatype":"string"},"type":"statement","id":"Q4260874$479C5D5F-AFFC-4CA2-9312-C3951CBA7572","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1450","hash":"e9db108701b9bea75800a5d5a3d86343adfb4d60","datavalue":{"value":"low density lipoproteins","type":"string"},"datatype":"string"},"type":"statement","id":"Q4260874$27D31E42-E2B6-445D-B730-98D2048F5BBA","rank":"normal"}],"P1460":[{"mainsnak":{"snaktype":"value","property":"P1460","hash":"57f7fea50d2ce1b39b695c4a1313582eed405e38","datavalue":{"value":{"entity-type":"item","numeric-id":5976449,"id":"Q5976449"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q4260874$DEB6FDAB-8ACD-4285-A3EB-4B49C84CC5EA","rank":"normal"}],"P1643":[{"mainsnak":{"snaktype":"value","property":"P1643","hash":"97b4efafaa70d0dcea184ee836621e9d9fd9010b","datavalue":{"value":{"entity-type":"item","numeric-id":3015820,"id":"Q3015820"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"cbed41169aacc8bea2c5af53bff8ba32fd7f6ce2","datavalue":{"value":{"amount":"+0.7982891798019409","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q4260874$8C95963A-8629-4C23-A2FE-8B2AB8B4E33C","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"6450b2b203a6abbea63d08a909645fbe33fcfde8","datavalue":{"value":{"entity-type":"item","numeric-id":4228047,"id":"Q4228047"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"8b84c45d1d24f77905a171edf505dae53de41f2d","datavalue":{"value":{"amount":"+0.797351598739624","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q4260874$89A7BBB4-5331-4A2D-833F-70D93FFCD6BC","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"2a7dd172dbbd1321f66145f96617df5ec55692a9","datavalue":{"value":{"entity-type":"item","numeric-id":839951,"id":"Q839951"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"ab0e656718d86be879b47fd5b7c8524ad8e5ca8c","datavalue":{"value":{"amount":"+0.7829422354698181","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q4260874$FEA3750A-30F7-4D29-8444-DD1A993E5545","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"80acf6ec93d18ceeab9ba42ec0372e26f0e95339","datavalue":{"value":{"entity-type":"item","numeric-id":3992626,"id":"Q3992626"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"af213fef7b745dcb088ec24bed1ff296fea7c5e6","datavalue":{"value":{"amount":"+0.775970458984375","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q4260874$39C560C8-E399-4FB9-A0DC-EDAA54EB4A8F","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P1643","hash":"6cbf5d6b8c0a80261b7de2aee5f2bda96232eb2d","datavalue":{"value":{"entity-type":"item","numeric-id":1969231,"id":"Q1969231"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P1659":[{"snaktype":"value","property":"P1659","hash":"88237dd78e06111147bb2d7005b25f0a0917c4ce","datavalue":{"value":{"amount":"+0.7719975113868713","unit":"1"},"type":"quantity"},"datatype":"quantity"}],"P1660":[{"snaktype":"value","property":"P1660","hash":"a327a09ea0305e98d5cf33bd4036320e19f2aed0","datavalue":{"value":{"entity-type":"item","numeric-id":6821328,"id":"Q6821328"},"type":"wikibase-entityid"},"datatype":"wikibase-item"}]},"qualifiers-order":["P1659","P1660"],"id":"Q4260874$B76CD08C-D139-4002-AD9F-14D08F6AB0F0","rank":"normal"}],"P1448":[{"mainsnak":{"snaktype":"value","property":"P1448","hash":"677fb7a87e6697831c66277cde2ddb3bae3edae1","datavalue":{"value":"In general, the term endocytosis refers to the process of internalization of substances through the cell membrane. In receptor-mediated endocytosis, large protein molecules called receptors project from the cell membrane and bind selectively to biologically active molecules called ligands. The ligand-receptor complexes are internalized by the invagination of specialized cell surface structures called coated pits. The research presented here is aimed at the theoretical exploration of certain aspects of the receptor mediated endocytic cycle for low density lipoproteins (LDL). The internalization of this ligand provides cholesterol for cell function. In section 2 we present the biological background. The theoretical methods are introduced in section 3. In Section 4 the mathematical model for the receptor mediated cycle for LDL in human fibroblastic cells under the considered assumptions is developed. The functional which gives the mean capture time for LDL receptors in coated pits is obtained in section 5. The formal analysis of the results is carried out in section 6. In a last section we discuss the implications of the derived results and illustrate the use of the model considering the experimentally obtained values for the parameters pertinent to the LDL system in human fibroblastic cells. For the entire collection see [Zbl 0899.00023].","type":"string"},"datatype":"string"},"type":"statement","id":"Q4260874$BF9F788D-7D63-47CB-88A6-2DE07CE7C2A3","rank":"normal"}]},"sitelinks":{"mardi":{"site":"mardi","title":"Publication:4260874","badges":[],"url":"https://portal.mardi4nfdi.de/wiki/Publication:4260874"}}}}}