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In biochemical reaction networks, a well-known polynomial model is the the steady state ideal. This model comes from the ordinary differential equations describing change of the concentrations in this kind of reaction networks. The problem of binomiality of steady state ideals is considered when the rate constants are viewed as parameters.  So, to study the binomiality of parametric steady state ideals, we need an effective test for being a binomial ideal. Moreover, one needs some algebraic tools to deal with parametric ideals. The problem of binomiality testing has been considered by several mathematicians and in particular a linear algebra based method has been described to solve this problem which seems to be efficient in practice. Furthermore, to study parametric ideals, the authors apply the concept of comprehensive Grobner bases introduced by Weispfenning. 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