{"entities":{"Q95864":{"pageid":97165,"ns":120,"title":"Item:Q95864","lastrevid":105501716,"modified":"2026-10-10T00:51:22Z","type":"item","id":"Q95864","labels":{"en":{"language":"en","value":"DrDimont"}},"descriptions":{"en":{"language":"en","value":"Drug Response Prediction from Differential Multi-Omics Networks"}},"aliases":{},"claims":{"P31":[{"mainsnak":{"snaktype":"value","property":"P31","hash":"438d0eef0223375d3a92def8ffc6a10a8bf1ca95","datavalue":{"value":{"entity-type":"item","numeric-id":57080,"id":"Q57080"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$A8F2B5E8-3994-4109-A981-86111682E056","rank":"normal"}],"P132":[{"mainsnak":{"snaktype":"value","property":"P132","hash":"c4c531ad1b89c5ba6464b86c76e97622abb245ef","datavalue":{"value":"0.1.4","type":"string"},"datatype":"string"},"type":"statement","qualifiers":{"P28":[{"snaktype":"value","property":"P28","hash":"d7678702b9c02727a1f0c88d72abf9470af5cdd7","datavalue":{"value":{"time":"+2022-09-23T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"}]},"qualifiers-order":["P28"],"id":"Q95864$D80BC44E-586C-4390-B074-C28F0741C016","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P132","hash":"954d5354d497f63bbdb6d95ed05a0ef7b6accda0","datavalue":{"value":"0.1.3","type":"string"},"datatype":"string"},"type":"statement","qualifiers":{"P28":[{"snaktype":"value","property":"P28","hash":"a56af58cfd4d3b017f8833425a5cd2b6e7283d16","datavalue":{"value":{"time":"+2022-05-17T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"}]},"qualifiers-order":["P28"],"id":"Q95864$948399FE-6060-4E78-9A7A-CBC722A5C349","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P132","hash":"abeebed34151d549c88a00beb5da85655d6f8061","datavalue":{"value":"0.1.6","type":"string"},"datatype":"string"},"type":"statement","qualifiers":{"P28":[{"snaktype":"value","property":"P28","hash":"dda8261b12e6ca5726a38c9d7e388258dec1ed34","datavalue":{"value":{"time":"+2025-11-08T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"}]},"qualifiers-order":["P28"],"id":"Q95864$97FE3814-838D-4A4B-9AD8-53BA135A8D39","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P132","hash":"b542975f358e64266fc8bf3287bc018a1e05a763","datavalue":{"value":"PACKAGES.rds","type":"string"},"datatype":"string"},"type":"statement","qualifiers":{"P28":[{"snaktype":"value","property":"P28","hash":"bdab782bc09c5c1d8687a0515dd3ffbe9dda94be","datavalue":{"value":{"time":"+2026-07-09T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"}]},"qualifiers-order":["P28"],"id":"Q95864$EBE09A7E-380E-42E8-9E31-AB0637E59057","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P132","hash":"35198eab11223bc0171ebe3e6bfa5244dea8002d","datavalue":{"value":"0.1.7","type":"string"},"datatype":"string"},"type":"statement","qualifiers":{"P28":[{"snaktype":"value","property":"P28","hash":"9d556298c74812728f22fa1afe6c0d082f991f8e","datavalue":{"value":{"time":"+2026-07-21T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"}]},"qualifiers-order":["P28"],"id":"Q95864$C428D7E7-D8D6-4E44-903C-5FFF39C51940","rank":"normal"}],"P16":[{"mainsnak":{"snaktype":"value","property":"P16","hash":"82551bef583972d0d354a42f422a4186dfafec69","datavalue":{"value":{"entity-type":"item","numeric-id":95763,"id":"Q95763"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$A0C25E22-B011-4D03-A9A9-F654ABB65D02","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"a91ee50eb2f548309c4787fce45afd529b8c9066","datavalue":{"value":{"entity-type":"item","numeric-id":95764,"id":"Q95764"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$91BF6723-3D99-43A1-A7A4-DA90E7D91ED9","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"6d9823cd4a4f7812411e35d0a8a38530338ba8d3","datavalue":{"value":{"entity-type":"item","numeric-id":95765,"id":"Q95765"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$82429F86-5359-4934-8D4B-FAE73F2DAEBB","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"75da0ff8939661e8f5e7f1c7274b3ca8460ead83","datavalue":{"value":{"entity-type":"item","numeric-id":95766,"id":"Q95766"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$EB629DC9-C706-472A-BCC1-066957420395","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P16","hash":"7bd732bae03488636262a79ef36530f234e1db3b","datavalue":{"value":{"entity-type":"item","numeric-id":95767,"id":"Q95767"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$9BD86828-E601-48C5-A284-DAE7469A0EEF","rank":"normal"}],"P19":[{"mainsnak":{"snaktype":"value","property":"P19","hash":"e54c36880ecc3fc30782131fc81c533475c76386","datavalue":{"value":{"entity-type":"item","numeric-id":95768,"id":"Q95768"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$91D11A75-F41D-4038-9F2D-23A55CB01DB6","rank":"normal"}],"P163":[{"mainsnak":{"snaktype":"value","property":"P163","hash":"798f7287b894eadb2b35f0ab871accc413b115fd","datavalue":{"value":{"entity-type":"item","numeric-id":56842,"id":"Q56842"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$8F6B4EDF-06CD-4EB8-B705-8FBCE049E20D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P163","hash":"b26fc7b7fb6977874892e45a4763e1c915d89707","datavalue":{"value":{"entity-type":"item","numeric-id":57086,"id":"Q57086"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P188":[{"snaktype":"value","property":"P188","hash":"072f25c604ffebd8f26c3d3aa8f7cf14d5868e69","datavalue":{"value":"https://cran.r-project.org/web/packages/DrDimont/LICENSE","type":"string"},"datatype":"url"}]},"qualifiers-order":["P188"],"id":"Q95864$E0B32055-3306-4148-9174-BC60C21FC7C1","rank":"normal"}],"P585":[{"mainsnak":{"snaktype":"value","property":"P585","hash":"cf0bb4b7afc6201510aff05bb1162df882cedbf3","datavalue":{"value":{"entity-type":"item","numeric-id":57301,"id":"Q57301"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$49AEB74B-CCFC-4280-8C6F-8FAC2477D044","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"7aac00570a74583c448c8c2a1fe16ed9aaeff406","datavalue":{"value":{"entity-type":"item","numeric-id":57179,"id":"Q57179"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$41A91876-8B71-4584-BB12-1686FE1F47CB","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"24c3e3d95d6aceb19323da214a060d1bb0535ab2","datavalue":{"value":{"entity-type":"item","numeric-id":57178,"id":"Q57178"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$08CE611D-8C33-48F5-B69A-99D203F38683","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"51fb9780d9ec9fcbaff0cba7840f3ec19b0b26fb","datavalue":{"value":{"entity-type":"item","numeric-id":25186,"id":"Q25186"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$647537C2-0C7B-43BB-9F6A-98311D394C6D","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"0d46eb3ad16db44b2ec612f745c082d76ccfffa0","datavalue":{"value":{"entity-type":"item","numeric-id":23242,"id":"Q23242"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$4735F202-F84B-41D1-B354-B799DE61C98F","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"4939bc71534d42a92193f0f48211425348e4c4ff","datavalue":{"value":{"entity-type":"item","numeric-id":19178,"id":"Q19178"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$A314719D-8A9B-4845-ADF9-4965702EDB40","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"2bed6a4011bec9a51018731544fa808ba481e21b","datavalue":{"value":{"entity-type":"item","numeric-id":43247,"id":"Q43247"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$F3D9F71C-9B0F-40D2-A023-873C588993FE","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"8727f06855176c36981e190c03808b62f2db192f","datavalue":{"value":{"entity-type":"item","numeric-id":31188,"id":"Q31188"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$173DD38B-545E-485F-A980-7F366AB44C72","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"2ee7437394063222d73a2d7c0725d30564fd3708","datavalue":{"value":{"entity-type":"item","numeric-id":31187,"id":"Q31187"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$381AC784-0243-4A3B-AF40-01816874B8A7","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"dbb2b5bebb047bfa0035de58c059f08733598b1b","datavalue":{"value":{"entity-type":"item","numeric-id":31185,"id":"Q31185"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$85EA943B-C83F-45E7-B430-F5C012DB5876","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"8baa5ed6156d07ff3c6e18db383632abb358c9f4","datavalue":{"value":{"entity-type":"item","numeric-id":31150,"id":"Q31150"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$527E9B8D-5975-4D3A-8DC1-78BAEC52ED17","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"61c3b0ee51d7a79f6fdfa763623807ee82244a95","datavalue":{"value":{"entity-type":"item","numeric-id":54216,"id":"Q54216"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$71130A04-B2C0-481F-AC1B-A2FB6C1CA706","rank":"normal"},{"mainsnak":{"snaktype":"value","property":"P585","hash":"6260c42fa99fac8786c033586e3e541237782d84","datavalue":{"value":{"entity-type":"item","numeric-id":40157,"id":"Q40157"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$091DCF59-E658-414C-B6CB-933D23352AEC","rank":"normal"}],"P223":[{"mainsnak":{"snaktype":"value","property":"P223","hash":"1283399706c0de48db74dd34e78791bd7ecd5952","datavalue":{"value":{"entity-type":"item","numeric-id":95863,"id":"Q95863"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$FD98E596-9590-4860-BE3C-26891E4E58FD","rank":"normal"}],"P229":[{"mainsnak":{"snaktype":"value","property":"P229","hash":"0eed1422e26a065a2e15cbe39766528742418e82","datavalue":{"value":"DrDimont","type":"string"},"datatype":"external-id"},"type":"statement","id":"Q95864$BE83C591-BE4F-4DDD-BE38-53B374CB69A2","rank":"normal"}],"P114":[{"mainsnak":{"snaktype":"value","property":"P114","hash":"251fd109c2cd8c1ee39b48cd109c9f4b1c9fcf5c","datavalue":{"value":{"entity-type":"item","numeric-id":13519,"id":"Q13519"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$98222C15-0DE0-4DAB-8060-1BD44803B80D","rank":"normal"}],"P1460":[{"mainsnak":{"snaktype":"value","property":"P1460","hash":"908c3454b3659c4b140ccce33c5aee31081edc8d","datavalue":{"value":{"entity-type":"item","numeric-id":5976450,"id":"Q5976450"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q95864$B41F506C-DDC9-4BD0-B252-DACA8E9A5758","rank":"normal"}],"P170":[{"mainsnak":{"snaktype":"value","property":"P170","hash":"feccb12c71aa72b1ad4d30dfcc9bb69d8598018e","datavalue":{"value":{"time":"+2026-07-21T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q95864$C21E41E1-8C7C-435A-8C7D-4E452538DECF","rank":"normal"}],"P342":[{"mainsnak":{"snaktype":"value","property":"P342","hash":"a0beaece152e3d4cfe5f01b8a4c02caff7e1e6cc","datavalue":{"value":{"entity-type":"item","numeric-id":56774,"id":"Q56774"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","qualifiers":{"P132":[{"snaktype":"value","property":"P132","hash":"d58e5b1027dfb6f2eb46f744a45ba1224fa0fc25","datavalue":{"value":"\u2265 3.5.0","type":"string"},"datatype":"string"}]},"qualifiers-order":["P132"],"id":"Q95864$CBAB91FB-9427-43D2-8580-10F1A15CA700","rank":"normal"}],"P1459":[{"mainsnak":{"snaktype":"value","property":"P1459","hash":"59e39607808908b256d7eba8aab7013d6f31c35f","datavalue":{"value":"While it has been well established that drugs affect and help  patients differently, personalized drug response predictions remain   challenging. Solutions based on single omics measurements have been proposed,   and networks provide means to incorporate molecular interactions into reasoning.   However, how to integrate the wealth of information contained in multiple omics   layers still poses a complex problem.   We present a novel network analysis pipeline, DrDimont, Drug response prediction   from Differential analysis of multi-omics networks. It allows for comparative   conclusions between two conditions and translates them into differential drug   response predictions. DrDimont focuses on molecular interactions. It establishes   condition-specific networks from correlation within an omics layer that are   then reduced and combined into heterogeneous, multi-omics molecular networks.   A novel semi-local, path-based integration step ensures integrative conclusions.   Differential predictions are derived from comparing the condition-specific   integrated networks. DrDimont's predictions are explainable, i.e., molecular   differences that are the source of high differential drug scores can be retrieved.  Our proposed pipeline leverages multi-omics data for differential predictions,  e.g. on drug response, and includes prior information on interactions.  The case study presented in the vignette uses data published by  Krug (2020) <doi:10.1016/j.cell.2020.10.036>. The package license applies only  to the software and explicitly not to the included data.","type":"string"},"datatype":"string"},"type":"statement","id":"Q95864$E247ECAD-679B-4009-B79A-91A61F1E00BF","rank":"normal"}]},"sitelinks":{"mardi":{"site":"mardi","title":"DrDimont","badges":[],"url":"https://portal.mardi4nfdi.de/wiki/DrDimont"}}}}}