scDiffCom (Q122749): Difference between revisions

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Property / last update
17 August 2021
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Property / cites work: scAgeCom: a murine atlas of age-related changes in intercellular communication inferred with the package scDiffCom / rank
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1.0.0
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publication date: 3 November 2023
Timestamp+2023-11-03T00:00:00Z
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3 November 2023
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Analysis tools to investigate changes in intercellular communication from scRNA-seq data. Using a Seurat object as input, the package infers which cell-cell interactions are present in the dataset and how these interactions change between two conditions of interest (e.g. young vs old). It relies on an internal database of ligand-receptor interactions (available for human, mouse and rat) that have been gathered from several published studies. Detection and differential analyses rely on permutation tests. The package also contains several tools to perform over-representation analysis and visualize the results. See Lagger, C. et al. (2023) <doi:10.1038/s43587-023-00514-x> for a full description of the methodology.
Property / description: Analysis tools to investigate changes in intercellular communication from scRNA-seq data. Using a Seurat object as input, the package infers which cell-cell interactions are present in the dataset and how these interactions change between two conditions of interest (e.g. young vs old). It relies on an internal database of ligand-receptor interactions (available for human, mouse and rat) that have been gathered from several published studies. Detection and differential analyses rely on permutation tests. The package also contains several tools to perform over-representation analysis and visualize the results. See Lagger, C. et al. (2023) <doi:10.1038/s43587-023-00514-x> for a full description of the methodology. / rank
 
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Property / author: Cyril Lagger / rank
 
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Property / author: Eugen Ursu / rank
 
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Property / copyright license: MIT license / rank
 
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Property / copyright license: File License / rank
 
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Property / cites work: scDiffCom: a tool for differential analysis of cell–cell interactions provides a mouse atlas of aging changes in intercellular communication / rank
 
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Property / MaRDI profile type: MaRDI software profile / rank
 
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links / mardi / namelinks / mardi / name
 

Latest revision as of 18:56, 12 March 2024

Differential Analysis of Intercellular Communication from scRNA-Seq Data
Language Label Description Also known as
English
scDiffCom
Differential Analysis of Intercellular Communication from scRNA-Seq Data

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    0.1.0
    17 August 2021
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    1.0.0
    3 November 2023
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    3 November 2023
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    Analysis tools to investigate changes in intercellular communication from scRNA-seq data. Using a Seurat object as input, the package infers which cell-cell interactions are present in the dataset and how these interactions change between two conditions of interest (e.g. young vs old). It relies on an internal database of ligand-receptor interactions (available for human, mouse and rat) that have been gathered from several published studies. Detection and differential analyses rely on permutation tests. The package also contains several tools to perform over-representation analysis and visualize the results. See Lagger, C. et al. (2023) <doi:10.1038/s43587-023-00514-x> for a full description of the methodology.
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