A stochastic model for the origin and treatment of tumors containing drug-resistant cells (Q1820076): Difference between revisions
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| Property / cites work: A mathematical model of the effects of drug resistance in cancer chemotherapy / rank | |||
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| Property / cites work: A model for the resistance of tumor cells to cancer chemotherapeutic agents / rank | |||
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| Property / cites work: The effect of cellular differentiation on the development of permanent drug resistance / rank | |||
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| Property / cites work: Q5624492 / rank | |||
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| Property / cites work: A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS / rank | |||
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Latest revision as of 17:56, 17 June 2024
scientific article
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | A stochastic model for the origin and treatment of tumors containing drug-resistant cells |
scientific article |
Statements
A stochastic model for the origin and treatment of tumors containing drug-resistant cells (English)
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1986
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A stochastic model for the chemotherapy of experimental tumors is presented. The focus of this model is on the presence of drug-resistant mutants and their influence on eventual treatment outcome. Equations are derived for the joint probability-generating function for the number of chemo-sensitive and chemo-resistant cells. The model is extended to two drugs and it is shown how the model may be used to make deductions regarding the optimum scheduling of therapy.
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Kolmogorov forward equations
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stochastic model
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chemotherapy of experimental tumors
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drug-resistant mutants
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joint probability-generating function
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chemo-sensitive and chemo-resistant cells
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optimum scheduling of therapy
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