Task:6684578

Community: MathModDB

computational task

linear task

Available identifiers

MaRDI QIDQ6684578

linear fit to determine the limiting reaction rate and michaelis constant, named after Barnet Woolf, Charles Samuel Hanes

List of contained entities

Hanes Woolf equation (uni uni reaction without product - irreversibility assumption)	$\frac{c_S}{v_0}=\frac{1}{V_{max,f}}{c}_S+\frac{K_S}{V_{max,f}}$
	$K_S$ represents Michaelis constant substrate (uni uni reaction - irreversibility assumption)
	$V_{max,f}$ represents limiting reaction rate (uni uni reaction - forward)
	$c_S$ represents substrate concentration
	$v_0$ represents initial reaction rate
Michaelis constant substrate (uni uni reaction - irreversibility assumption)	$K_S\equiv \frac{k_2}{k_1}$	output
	$k_1$ represents reaction rate constant
	$k_2$ represents reaction rate constant
	$K_S$ represents Michaelis constant substrate (uni uni reaction - irreversibility assumption)
initial reaction rate
limiting reaction rate (uni uni reaction - forward)	$V_{max,f}\equiv k_2{c}_{E_0}$	output
	$c_{E_0}$ represents enzyme concentration
	$k_2$ represents reaction rate constant
	$V_{max,f}$ represents limiting reaction rate (uni uni reaction - forward)
substrate concentration

Further items linking to linear parameter estimation (uni uni reaction without product - Hanes Woolf model - irreversibility assumption)

Item	Property
linear parameter estimation of enzyme kinetics	specialized by
nonlinear parameter estimation (uni uni reaction without product - Michaelis Menten model - irreversibility assumption)	linearized by
uni uni reaction (Hanes Woolf model without product - irreversibility assumption)	used by

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