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A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija (2019) <doi:10.1186/s13059-019-1874-1>, and Choudhary and Satija (2022) <doi:10.1186/s13059-021-02584-9> for more details.
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Latest revision as of 18:55, 12 March 2024

Variance Stabilizing Transformations for Single Cell UMI Data
Language Label Description Also known as
English
sctransform
Variance Stabilizing Transformations for Single Cell UMI Data

    Statements

    0.3.5
    21 September 2022
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    0.1.0
    18 November 2018
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    0.2.0
    12 April 2019
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    0.2.1
    17 December 2019
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    0.3.1
    8 October 2020
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    0.3.2
    16 December 2020
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    0.3.3
    13 January 2022
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    0.3.4
    21 August 2022
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    0.3
    20 September 2020
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    0.4.0
    19 September 2023
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    0.4.1
    19 October 2023
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    19 October 2023
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    A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija (2019) <doi:10.1186/s13059-019-1874-1>, and Choudhary and Satija (2022) <doi:10.1186/s13059-021-02584-9> for more details.
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