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Revision as of 11:56, 7 March 2024

Analysis of Omics Data in Observational Studies
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English
epiomics
Analysis of Omics Data in Observational Studies

    Statements

    1.0.0
    15 March 2023
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    0.0.1
    9 January 2023
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    1.1.0
    26 February 2024
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    26 February 2024
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    A collection of fast and flexible functions for analyzing omics data in observational studies. Multiple different approaches for integrating multiple environmental/genetic factors, omics data, and/or phenotype data are implemented. This includes functions for performing omics wide association studies with one or more variables of interest as the exposure or outcome; a function for performing a meet in the middle analysis for linking exposures, omics, and outcomes (as described by Chadeau-Hyam et al., (2010) <doi:10.3109/1354750X.2010.533285>); and a function for performing a mixtures analysis across all omics features using quantile-based g-Computation (as described by Keil et al., (2019) <doi:10.1289/EHP5838>).
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