Propagation and control of gene expression noise with non-linear translation kinetics

DOI10.1016/j.jtbi.2017.07.006zbMath1382.92154OpenAlexW2735751754WikidataQ46335713 ScholiaQ46335713MaRDI QIDQ1705274

J. David Van Dyken

Publication date: 15 March 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2017.07.006

zbMATH Keywords

stochastic processMichaelis-Mentenlinear noise approximationchemical master equationcellular robustnessmRNA noiseprotein noise

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

Uses Software

• Cellerator

Cites Work

• On the validity of the steady state assumption of enzyme kinetics
• Noise slows the rate of Michaelis-Menten reactions
• Extending the quasi-steady state approximation by changing variables
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