The effect of scale-free topology on the robustness and evolvability of genetic regulatory networks

DOI10.1016/j.jtbi.2010.08.006zbMath1410.92065arXiv1005.4342WikidataQ84704220 ScholiaQ84704220MaRDI QIDQ1732926

Matthew A. Smith, Jonathan P. K. Doye, Ard A. Louis, Sam F. Greenbury, Iain G. Johnston

Publication date: 26 March 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1005.4342

zbMATH Keywords

evolvability; robustness; gene regulatory networks; scale-free; Boolean threshold networks

Mathematics Subject Classification ID

05C90: Applications of graph theory

92D10: Genetics and epigenetics

92C42: Systems biology, networks

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Cites Work

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• Evolution of a population of random Boolean networks
• Boolean dynamics of networks with scale-free topology
• Reliability of regulatory networks and its evolution
• Comparing different ODE modelling approaches for gene regulatory networks
• The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in \textit{Drosophila melanogaster}
• Robustness and evolvability in genetic regulatory networks
• Emergence of Scaling in Random Networks
• Evolution of gene networks by gene duplications: a mathematical model and its implications on genome organization.
• Neural networks and physical systems with emergent collective computational abilities.