Modeling quasispecies and drug resistance in hepatitis C patients treated with a protease inhibitor

DOI10.1007/S11538-012-9736-YzbMath1251.92021OpenAlexW2054896384WikidataQ36104288 ScholiaQ36104288MaRDI QIDQ1758099

Ruy M. Ribeiro, Alan S. Perelson, Libin Rong

Publication date: 7 November 2012

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3400267

zbMATH Keywords

mutationfitnessquasispeciesdirect-acting antiviral agentstelaprevir

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Medical applications (general) (92C50)

Related Items (9)

Qualitative behaviour of a stochastic hepatitis C epidemic model in cellular level ⋮ A within-host drug resistance model with continuous state-dependent viral strains ⋮ Modeling the XBB strain of SARS-CoV-2: competition between variants and impact of reinfection ⋮ A multi-strain model with asymptomatic transmission: application to COVID-19 in the US ⋮ Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents ⋮ HIV/HCV coinfection model: a fractional-order perspective for the effect of the HIV viral load ⋮ Existence and Dynamics of Strains in a Nonlocal Reaction-Diffusion Model of Viral Evolution ⋮ Viral Kinetic Modeling of Chronic Hepatitis C and B Infection ⋮ Bifurcation analysis and chaos for a double-strains HIV coinfection model with intracellular delays, saturated incidence and logistic growth

Cites Work

• Emergence of HIV-1 drug resistance during antiretroviral treatment
• Mathematical analysis of the global dynamics of a model for HIV infection of CD4\(^{+}\) T cells
• Analysis of Hepatitis C Virus Infection Models with Hepatocyte Homeostasis
• Multistrain virus dynamics with mutations: a global analysis

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