Joint analysis of SNP and gene expression data in genetic association studies of complex diseases

DOI10.1214/13-AOAS690zbMath1454.62343arXiv1404.6423OpenAlexW3098193298WikidataQ30800044 ScholiaQ30800044MaRDI QIDQ2453676

Tyler J. Vanderweele, Xihong Lin, Yen-Tsung Huang

Publication date: 10 June 2014

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1404.6423

zbMATH Keywords

score testmixed modelscausal inferencemediation analysisdata intergrationSNP set analysisvariance component set

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (8)

Joint analysis of SNP and gene expression data in genetic association studies of complex diseases ⋮ Hypothesis test of mediation effect in causal mediation model with high‐dimensional continuous mediators ⋮ Bayesian Approaches for Large Biological Networks ⋮ Power of testing for exposure effects under incomplete mediation ⋮ Robust Score Tests With Missing Data in Genomics Studies ⋮ Multiple testing approaches for hypotheses in integrative genomics ⋮ Varying Coefficient Mediation Model and Application to Analysis of Behavioral Economics Data ⋮ Mediation analysis for common binary outcomes

Uses Software

• IMPUTE
• AS 155

Cites Work

• Unnamed Item
• Conceptual issues concerning mediation, interventions and composition
• Identification, inference and sensitivity analysis for causal mediation effects
• Bayesian inference for causal effects: The role of randomization
• Joint analysis of SNP and gene expression data in genetic association studies of complex diseases
• A Score Based Approach to Wild Bootstrap Inference
• Models for Longitudinal Data: A Generalized Estimating Equation Approach
• Algorithm AS 155: The Distribution of a Linear Combination of χ 2 Random Variables
• A resampling method based on pivotal estimating functions
• Variance component testing in generalised linear models with random effects
• A Direct Approach to False Discovery Rates

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