A moment-based method for estimating the proportion of true null hypotheses and its application to microarray gene expression data

DOI10.1093/biostatistics/kxm002zbMath1267.62105OpenAlexW2164230915WikidataQ31095547 ScholiaQ31095547MaRDI QIDQ2838991

Yinglei Lai

Publication date: 4 July 2013

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/kxm002

zbMATH Keywords

moment estimator

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Paired and multiple comparisons; multiple testing (62J15) Systems biology, networks (92C42)

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A Bernstein-type estimator for decreasing density with application to \(p\)-value adjustments ⋮ Estimating the proportion of true null hypotheses using the pattern of observedp-values ⋮ False Discovery Rate Estimation for Frequentist Pharmacovigilance Signal Detection Methods ⋮ A multivariate version of the Benjamini-Hochberg method ⋮ Improved Estimation of the Noncentrality Parameter Distribution from a Large Number of t‐Statistics, with Applications to False Discovery Rate Estimation in Microarray Data Analysis

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