Sequential Testing to Guarantee the Necessary Sample Size in Clinical Trials

DOI10.1080/03610920902947584zbMath1175.62085OpenAlexW2057066796MaRDI QIDQ3645030

Andrew. L. Rukhin

Publication date: 16 November 2009

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610920902947584

zbMATH Keywords

clinical trialsPoisson processlocally optimal testBorel distributionLagrangian Poisson distributionenrollment process

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Inference from stochastic processes (62M99) Sequential statistical analysis (62L10) Optimal stopping in statistics (62L15)

Cites Work

• Asymptotic optimal sequential estimation: The Poisson case
• Dynkin's identity applied to Bayes sequential estimation of a Poisson process rate
• Some recent results on the distributions of stopping times of compound Poisson processes with linear boundaries
• One-Sided Sequential Stopping Boundaries for Clinical Trials: A Decision- Theoretic Approach
• Distributions of stopping times for poisson processes with linear boundaries
• Multi-Center Clinical Trials with Random Enrollment: Theoretical Approximations
• First crossing of basic counting processes with lower non-linear boundaries: A unified approach through pseudopolynomials (I)
• Statistical Methods Related to the Law of the Iterated Logarithm
• Bayesian sequential estimation of a Poisson process rate

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