Rhythmomimetic Drug Delivery: Modeling, Analysis, and Numerical Simulation

DOI10.1137/16M1067007zbMath1376.34050arXiv1512.05758OpenAlexW2963254666MaRDI QIDQ5346780

Yoichiro Mori, Lingxing Yao, M. Carme Calderer, Ronald A. Siegel

Publication date: 29 May 2017

Published in: SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1512.05758

zbMATH Keywords

hysteresisweak solutionlimit cyclechemical reactioninertial manifoldmultiscalepolyelectrolyte gelcompetitive dynamical systemvolume transition

Mathematics Subject Classification ID

Topological structure of integral curves, singular points, limit cycles of ordinary differential equations (34C05) Bifurcation theory for ordinary differential equations (34C23) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Qualitative investigation and simulation of ordinary differential equation models (34C60) Invariant manifolds for ordinary differential equations (34C45) Multiple scale methods for ordinary differential equations (34E13) Hysteresis for ordinary differential equations (34C55)

Related Items (2)

Experiments, modelling, and simulations for a gel bonded to a rigid substrate ⋮ An integrate-and-fire model for pulsatility in the neuroendocrine system

Cites Work

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• Global analysis of a model pulsing drug delivery oscillator based on chemomechanical feedback with hysteresis
• Systems of Differential Equations That are Competitive or Cooperative. IV: Structural Stability in Three-Dimensional Systems
• Systems of Differential Equations that are Competitive or Cooperative II: Convergence Almost Everywhere
• Systems of Differential Equations Which Are Competitive or Cooperative: I. Limit Sets
• False bifurcations in chemical systems: canards
• Virus Dynamics: A Global Analysis
• The Forced van der Pol Equation II: Canards in the Reduced System

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