wnl
Software:61825
Minimization Tool for Pharmacokinetic-Pharmacodynamic Data Analysis
Last update: 22 February 2024
Copyright license: GNU General Public License, version 3.0
Software version identifier: 0.7.2, 0.7.3, 0.3.1, 0.3.2, 0.3.3, 0.4.0, 0.4.1, 0.5.0, 0.5.1, 0.6.0, 0.6.1, 0.6.2, 0.6.3, 0.6.4, 0.7.0, 0.7.1, 0.8.0
This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.
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