BioM2

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Software:5978111



CRANBioM2MaRDI QIDQ5978111

Biologically Explainable Machine Learning Framework

Shunjie Zhang

Last update: 11 January 2024

Software version identifier: 1.0.1, 1.0.2, 1.0, 1.0.3


Copyright license: MIT license, File License

Biologically Explainable Machine Learning Framework for Phenotype Prediction using omics data described in Chen and Schwarz (2017) <arXiv:1712.0036v1>.Identifying reproducible and interpretable biological patterns from high-dimensional omics data is a critical factor in understanding the risk mechanism of complex disease. As such, explainable machine learning can offer biological insight in addition to personalized risk scoring.In this process, a feature space of biological pathways will be generated, and the feature space can also be subsequently analyzed using WGCNA (Described in Horvath and Zhang (2005) <doi:10.2202/1544-6115.1128> and Langfelder and Horvath (2008) <doi:10.1186/1471-2105-9-559> ) methods.