TFactSR

Enrichment Approach to Predict Which Transcription Factors are Regulated

Last update: 31 August 2023

Copyright license: GNU General Public License, version 3.0

Software version identifier: 0.99.0

Description

R implementation of 'TFactS' to predict which are the transcription factors (TFs), regulated in a biological condition based on lists of differentially expressed genes (DEGs) obtained from transcriptome experiments. This package is based on the 'TFactS' concept by Essaghir et al. (2010) <doi:10.1093/nar/gkq149> and expands it. It allows users to perform 'TFactS'-like enrichment approach. The package can import and use the original catalogue file from the 'TFactS' as well as users' defined catalogues of interest that are not supported by 'TFactS' (e.g., Arabidopsis).

Cites work

Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

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