Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials (Q4335635)

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scientific article; zbMATH DE number 1005954
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English
Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials
scientific article; zbMATH DE number 1005954

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    Incorporating Toxicity Considerations Into the Design of Two-Stage Phase II Clinical Trials (English)
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    12 June 1997
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    two-stage clinical trials
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    phase II trials
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    early stopping
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    Simon designs
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    multiple endpoints
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    group sequential designs
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    clinical response
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    toxicity
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    maximum expected accrual
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    control of error rates
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