Pharmacokinetically guided optimum adaptive dose selection in early phase clinical trials (Q1654244)

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Pharmacokinetically guided optimum adaptive dose selection in early phase clinical trials
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    Pharmacokinetically guided optimum adaptive dose selection in early phase clinical trials (English)
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    7 August 2018
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    area under the concentration curve
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    continuation ratio model
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    \(D\)-optimum sampling times
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    one-compartment pharmacokinetic model
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    population pharmacokinetics
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