bi bi reaction Ping Pong mechanism Michaelis Menten model with products 1 and 2 (steady state assumption)

Community: MathModDB

deterministic model	dimensional model	mathematical model	nonlinear model	static model

Available identifiers

MaRDI QIDQ6675347

bi bi reaction Michaelis Menten model following a ping-pong mechanism with products 1 and 2 formulated via the steady state assumption, named after Leonor Michaelis, Maud Menten

List of contained entities

Michaelis Menten equation (bi bi reaction ping pong with products 1 and 2 - Michaelis Menten model - steady state assumption)	$v_{0} = \frac{V_{1} V_{2} (c_{S_{1}} c_{S_{2}} - \frac{c_{P_{1}} c_{P_{2}}}{K_{e q}})}{V_{2} K_{S_{2}} c_{S_{1}} + V_{2} K_{S_{1}} c_{S_{2}} + \frac{V_{1} K_{P_{2}}}{K_{e q}} c_{P_{2}} + \frac{V_{1} K_{P_{1}}}{K_{e q}} c_{P_{2}} + V_{2} c_{S_{1}} c_{S_{2}} + \frac{V_{1} K_{P_{2}}}{K_{i S_{1}} K_{e q}} c_{S_{1}} c_{P_{1}} + \frac{V_{1}}{K_{e q}} c_{P_{1}} c_{P_{2}} + \frac{V_{2} K_{S_{1}}}{K_{i P_{2}}} c_{S_{2}} c_{P_{2}}}$
	$K_{P_{1}}$ represents Michaelis constant
	$K_{P_{2}}$ represents Michaelis constant
	$K_{S_{1}}$ represents Michaelis constant
	$K_{S_{2}}$ represents Michaelis constant
	$K_{e q}$ represents equilibrium constant
	$K_{i P_{1}}$ represents inhibition constant
	$K_{i P_{2}}$ represents inhibition constant
	$K_{i S_{1}}$ represents inhibition constant
	$K_{i S_{2}}$ represents inhibition constant
	$V_{1}$ represents reaction rate
	$V_{2}$ represents reaction rate
	$c_{P_{1}}$ represents concentration
	$c_{P_{2}}$ represents concentration
	$c_{S_{1}}$ represents concentration
	$c_{S_{2}}$ represents concentration
	$v_{0}$ represents reaction rate

initial product 1 concentration (bi bi reaction ping pong with product 1 - Michaelis Menten model)	$c_{P_{1}} (t = 0) = c_{P_{1, 0}}$	initial condition
	$c_{P_{1}}$ represents concentration
	$t$ represents time

initial product 2 concentration (bi bi reaction ping pong with product 2 - Michaelis Menten model)	$c_{P_{2}} (t = 0) = c_{P_{2, 0}}$	initial condition
	$c_{P_{2}}$ represents concentration
	$t$ represents time

initial substrate 1 concentration (bi bi reaction ping pong - Michaelis Menten model)	$c_{S_{1}} (t = 0) = c_{S_{1, 0}}$	initial condition
	$c_{S_{1}}$ represents concentration
	$t$ represents time

initial substrate 2 concentration (bi bi reaction ping pong - Michaelis Menten model)	$c_{S_{2}} (t = 0) = c_{S_{2, 0}}$	initial condition
	$c_{S_{2}}$ represents concentration
	$t$ represents time

law of mass action	$v = k \prod_{i = 1}^{n} c_{i}$
	$c_{i}$ represents concentration
	$k$ represents reaction rate constant
	$n$ represents molecularity
	$v$ represents reaction rate

mass balance	$δ_{t} + \nabla F = 0$

List of computational tasks

nonlinear parameter estimation of enzyme kinetics
parameter estimation of enzyme kinetics

List of assumptions

steady state assumption

Further items linking to bi bi reaction Ping Pong mechanism Michaelis Menten model with products 1 and 2 (steady state assumption)

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initial reaction rate of bi bi reaction following ping pong mechanism with products 1 and 2	modelled by

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