bi bi reaction Theorell-Chance mechanism Michaelis Menten model with product 2 (steady state assumption)

Community: MathModDB

deterministic model	mathematical model	nonlinear model	static model

Available identifiers

MaRDI QIDQ6675350

bi bi reaction Michaelis Menten model following a Theorell-Chance mechanism with product 2 formulated via the steady state assumption, named after Britton Chance, Hugo Theorell, Leonor Michaelis, Maud Menten

List of contained entities

Michaelis Menten equation (bi bi reaction Theorell-Chance with product 2 - Michaelis Menten model - steady state assumption)	$v_{0} = \frac{V_{1} c_{S_{1}} c_{S_{2}}}{K_{i S_{1}} K_{S_{2}} + K_{S_{2}} c_{S_{1}} + K_{S_{1}} c_{S_{2}} + c_{S_{1}} c_{S_{2}} + \frac{K_{i S_{1}} K_{S_{2}}}{K_{i P_{2}}} c_{P_{2}} + \frac{K_{S_{1}}}{K_{i P_{2}}} c_{S_{2}} c_{P_{2}}}$
	$K_{S_{1}}$ represents Michaelis constant
	$K_{S_{2}}$ represents Michaelis constant
	$K_{i P_{2}}$ represents inhibition constant
	$K_{i S_{1}}$ represents inhibition constant
	$V_{1}$ represents reaction rate
	$c_{P_{2}}$ represents concentration
	$c_{S_{1}}$ represents concentration
	$c_{S_{2}}$ represents concentration
	$v_{0}$ represents reaction rate

initial product 1 concentration (bi bi reaction Theorell-Chance without product 1 - Michaelis Menten model)	$c_{P_{1}} (t = 0) = 0$	initial condition
	$c_{P_{1}}$ represents concentration
	$t$ represents time

initial product 2 concentration (bi bi reaction Theorell-Chance with product 2 - Michaelis Menten model)	$c_{P_{2}} (t = 0) = c_{P_{2, 0}}$	initial condition
	$c_{P_{2}}$ represents concentration
	$t$ represents time

initial substrate 1 concentration (bi bi reaction Theorell-Chance - Michaelis Menten model)	$c_{S_{1}} (t = 0) = c_{S_{1, 0}}$	initial condition
	$c_{S_{1}}$ represents concentration
	$t$ represents time

initial substrate 2 concentration (bi bi reaction Theorell-Chance - Michaelis Menten model)	$c_{S_{2}} (t = 0) = c_{S_{2, 0}}$	initial condition
	$c_{S_{2}}$ represents concentration
	$t$ represents time

law of mass action	$v = k \prod_{i = 1}^{n} c_{i}$
	$c_{i}$ represents concentration
	$k$ represents reaction rate constant
	$n$ represents molecularity
	$v$ represents reaction rate

mass balance	$δ_{t} + \nabla F = 0$

List of computational tasks

nonlinear parameter estimation of enzyme kinetics

List of assumptions

steady state assumption

Further items linking to bi bi reaction Theorell-Chance mechanism Michaelis Menten model with product 2 (steady state assumption)

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bi bi reaction Theorell-Chance mechanism (ODE model)	specialized by
initial reaction rate of bi bi reaction following Theorell-Chance mechanism with product 2	modelled by

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