uni uni reaction (Eadie Hofstee model without product - rapid equilibrium assumption)

Community: MathModDB

deterministic model

linear model

mathematical model

static model

Available identifiers

MaRDI QIDQ6675399

uni uni reaction Eadie Hofstee model without product via the rapid equilibrium assumption, named after Barend Hendrik Jan Hofstee, George Sharpe Eadie

List of contained entities

Eadie Hofstee equation (uni uni reaction without product - rapid equilibrium assumption)	$v_0=V_{max,f}-K_S\frac{v_0}{c_S}$
	$K_S$ represents Michaelis constant substrate (uni uni reaction - rapid equilibrium assumption)
	$V_{max,f}$ represents limiting reaction rate (uni uni reaction - forward)
	$c_S$ represents substrate concentration
	$v_0$ represents initial reaction rate
enzyme conservation	$c_{E_0}=c_E+c_{EX}$
	$c_{EX}$ represents complexed enzyme concentration
	$c_{E_0}$ represents enzyme concentration
	$c_E$ represents enzyme concentration
initial product concentration (uni uni reaction without product)	$c_P(t=0)=0$	initial condition
	$c_P$ represents product concentration
	$t$ represents time
initial substrate concentration (uni uni reaction)	$c_S(t=0)=c_{S_0}$	initial condition
	$c_S$ represents substrate concentration
	$t$ represents time
law of mass action	$v=k\prod _{i=1}^n{c}_i$
	$c_i$ represents concentration
	$k$ represents reaction rate constant
	$n$ represents molecularity
	$v$ represents reaction rate
mass balance	${\delta }_t+\mathrm{\nabla }F=0$

List of computational tasks

linear parameter estimation (uni uni reaction without product - Eadie Hofstee model - rapid equilibrium assumption)

List of assumptions

rapid equilibrium assumption

Described at:

Non-Inverted Versus Inverted Plots in Enzyme Kinetics	(invention)
The inhibition of cholinesterase by physostigmine and prostigmine	(invention)

Further items linking to uni uni reaction (Eadie Hofstee model without product - rapid equilibrium assumption)

Item	Property
initial reaction rate of uni uni reaction without product	modelled by
uni uni reaction (Michaelis Menten model without product - rapid equilibrium assumption)	linearized by
uni uni reaction (ODE model)	specialized by

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