uni uni reaction with competitive partial inhibition (Q6684687)

Enzyme (E) and Substrate (S) form an enzyme-substrate complex (ES), which catalyzes the formation of product (P). Rates for complex formation and dissociation are k₁ and k₋₁, k₂ is the rate of the rate-determining enzymatic step of product formation. Free enzyme and the enzyme-substrate complex may bind an inhibitor (I) to form an enzyme-inhibitor (EI) and enzyme-inhibitor-substrate complex (EIS) with k₃ or k₋₃ and k₄ or k₋₄ as rates of inhibitor complex formation and depletion. Enzyme-inhibitor complex and enzyme-inhibitor-substrate convert into each other with rates k₅ and k₋₅. From the enzyme-inhibitor-substrate complex product is formed with rate k₂. Properly this is a mixed partial inhibition in which the inhibitor does not affect the turnover rate.