A Simulation-based Comparison Between Parametric and Nonparametric Estimation Methods in PBPK Models

DOI10.1163/1569394053583748MaRDI QIDQ4663924zbMATH OpenOpenAlexFDO

Authors Yanyuan Ma, Laura K. Potter, H. Thomas Banks

Publication date 4 April 2005

Full work available at URL http://www.lib.ncsu.edu/resolver/1840.4/456

zbMATH Keywords

ordinary differential equationsProhorov metric framework

Mathematics Subject Classification ID

Point estimation (62F10) Nonparametric estimation (62G05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05) Numerical analysis or methods applied to Markov chains (65C40) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• Comparison of nonparametric methods in nonlinear mixed effects models
• Parameter estimation of population pharmacokinetic models with stochastic differential equations: implementation of an estimation algorithm
• Nonparametric estimation in nonlinear mixed effects models
• Comparison of Frequentist and Bayesian Confidence Analysis Methods on a Viscoelastic Stenosis Model
• Comparison of simulation-based algorithms for parameter estimation and state reconstruction in nonlinear state-space models

Cited in

(1)

• An example of model structure differences using sensitivity analyses in physiologically based pharmacokinetic models of trichloroethylene in humans

This page was built for publication: A Simulation-based Comparison Between Parametric and Nonparametric Estimation Methods in PBPK Models

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q4663924)