A computational study of alternate SELEX

DOI10.1007/S11538-014-9954-6MaRDI QIDQ467699zbMATH OpenOpenAlexWikidataFDO

Authors Yeon-Jung Seo, Marit Nilsen-Hamilton, Howard A. Levine

Publication date 5 November 2014

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s11538-014-9954-6

zbMATH Keywords

specificityaffinityrelative efficiencyalternate SELEXnegative SELEX

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

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• Mathematical consideration of massive estimation of dissociation rate constant for genotype-phenotype linking molecules bound to targets through washing/selection and next-generation sequencing
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• Theoretical consideration of selective enrichment in in vitro selection: optimal concentration of target molecules
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• High affinity extremes in combinatorial libraries and repertoires
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• scientific article; zbMATH DE number 3909606 (Why is no real title available?)
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• Selective phenome growth adapted \(N K\) model: a novel landscape to represent aptamer ligand binding
• A discrete dynamical system arising in molecular biology
• Estimation of statistical binding properties of ligand population during in vitro selection based on population dynamics theory

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