A stochastic model of fragment formation when DNA replicates

DOI10.2307/3215025MaRDI QIDQ4305668zbMATH OpenOpenAlexFDO

Authors Richard Cowan, Sung Nok Chiu

Publication date 3 November 1994

Published in Journal of Applied Probability (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/3215025

zbMATH Keywords

DNAenzymesislands of newly replicated DNAOkazaki fragmentsPoisson processrandom locationrenewal equationreplication

Mathematics Subject Classification ID

Applications of renewal theory (reliability, demand theory, etc.) (60K10) Biochemistry, molecular biology (92C40) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Protein sequences, DNA sequences (92D20)

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• Some probability distributions in modelling DNA replication
• Wellposedness of a DNA replication model based on a nucleation-growth process
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• A limit theorem for the replication time of a DNA molecule
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• Modeling and analysis of DNA replication
• Stochastic chemical reaction networks with discontinuous limits and AIMD processes

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