Action potential propagation model

propagation of the action potential

continuous-space model, continuous-time model, deterministic model, dynamic model, mathematical model

MaRDI QIDQ6674954FDOCommunityMathModDB

Description

Accounts for the propagation of the action potential. Necessary because Subcellular model only considers isolated processes in one sacomere.

Contained entity(-ies)

monodomain equation for action potential propagation	$\frac{\partial V_{\text{m}}^{\text{f}}}{\partial t}=\frac{1}{C_{\text{m}}^{\text{f}}}(\frac{1}{A_{\text{m}}}{\sigma }_{\text{eff}}\frac{{\partial }^2{V}_{\text{m}}^{\text{f}}}{\partial s^2}-I_{\text{ion}}(V_{\text{m}}^{\text{f}},𝐲)+S(V_{\text{m}}^{\text{s}}))\text{in}{\mathrm{\Omega }}_f$
	$C_{\mathrm{m}}^{\mathrm{f}}$ represents membrane capacitance
	$I_{\mathrm{i}\mathrm{o}\mathrm{n}}$ represents ion current
	$V_{\text{m}}^{\text{f}}$ represents membrane potential
	${\sigma }_{\mathrm{e}\mathrm{f}\mathrm{f}}$ represents effective conductivity
	$t$ represents time
	$\mathbf{\text{𝐲}}$ represents state variable
	$s$ represents position vector
	$A_m$ represents surface-area-to-volume ratio

Reference(s)

Coupled simulations and parameter inversion for neural system and electrophysiological muscle models

(science project)

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