An Optimal Control Problem Subject to Strong Solutions of Chemotaxis-Consumption Models

DOI10.1137/23M1553637MaRDI QIDQ6057801zbMATH OpenOpenAlexFDO

Authors Francisco Guillén-González, André Luiz Corrêa Vianna Filho

Publication date 26 October 2023

Published in SIAM Journal on Control and Optimization (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2302.07766

zbMATH Keywords

chemotaxisconsumptionLagrange multiplieroptimal controlregularity criterionstrong solution

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Existence theories for optimal control problems involving partial differential equations (49J20) Optimality conditions for problems involving partial differential equations (49K20) Regularity of solutions in optimal control (49N60) Variational principles of physics (49S05) Cell movement (chemotaxis, etc.) (92C17)

Abstract: In the present work we investigate a bilinear optimal control problem associated to the following chemotaxis-consumption model in a bounded domain $Omegasubsetmathbb{R}^3$ during a time interval $(0,T)$: ${\displaystyle }$partial_t u - Delta u = -

abla cdot (u

abla v), quad partial_t v - Delta v = - u^s v + f v 1_{Omega_c}${\displaystyle }$ with $sgeq1$, endowed with isolated boundary conditions and initial conditions for $(u,v)$, $u$ being the cell density, $v$ the chemical concentration and $f$ the bilinear control acting in a subdomain $Omeg{a}_{c}subsetOmega$. The existence of weak solutions $(u,v)$ to this model given $fin{L}^q((0,T)imesOmega)$, for some $q>5/2$, has been proved in cite{guillen2022optimal}. In this work the optimal control problem is studied in a strong solution setting. First we prove that the regularity criterion $u^s,fin{L}^q((0,T)imesOmega)$ allows us to get existence and uniqueness of global-in-time strong solutions. In the sequel, we show the existence of a global optimal solution. Finally, using a Lagrange multipliers theorem, we establish first order optimality conditions for any local optimal solution, proving existence, uniqueness and regularity of the associated Lagrange multipliers.

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Cited in

(6)

• Optimal control related to weak solutions of a chemotaxis-consumption model
• An optimal control problem of a 2D-attraction-repulsion chemotaxis system
• A stationary chemo-repulsion system with nonlinear production and a bilinear optimal control problem related
• A review on the analysis and optimal control of chemotaxis-consumption models
• Bilinear optimal control of a reaction-diffusion equation: overcoming boundedness constraints on controls
• On a bi-dimensional chemo-repulsion model with nonlinear production and a related optimal control problem

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