An efficient basket trial design

DOI10.1002/SIM.7227MaRDI QIDQ6999296zbMATH OpenFDO

Authors Kristen M. Cunanan, Alexia Iasonos, Ronglai Shen, Colin B. Begg, Mithat Gönen

Publication date 9 April 2025

Published in Statistics in Medicine (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/SIM.7227

zbMATH Keywords

basket trialsmultiple comparisonsphase II clinical trialspower

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites work

• Adaptive Two-Stage Designs for Single-Arm Phase IIA Cancer Clinical Trials

Cited in

(5)

• Leveraging information from secondary endpoints to enhance dynamic borrowing across subpopulations
• Bayesian basket trial design with exchangeability monitoring
• Bayesian safety and futility monitoring in phase II trials using one utility-based rule
• A Bayesian decision-theoretic approach to multiple testing in basket trials
• Frequentist identification of effective baskets via the generalized information criteria in oncology phase 2 trials

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