An improved computer vision method for white blood cells detection
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Abstract: The automatic detection of White Blood Cells (WBC) still remains as an unsolved issue in medical imaging. The analysis of WBC images has engaged researchers from fields of medicine and computer vision alike. Since WBC can be approximated by an ellipsoid form, an ellipse detector algorithm may be successfully applied in order to recognize them. This paper presents an algorithm for the automatic detection of WBC embedded into complicated and cluttered smear images that considers the complete process as a multi-ellipse detection problem. The approach, based on the Differential Evolution (DE) algorithm, transforms the detection task into an optimization problem where individuals emulate candidate ellipses. An objective function evaluates if such candidate ellipses are really present in the edge image of the smear. Guided by the values of such function, the set of encoded candidate ellipses (individuals) are evolved using the DE algorithm so that they can fit into the WBC enclosed within the edge-only map of the image. Experimental results from white blood cell images with a varying range of complexity are included to validate the efficiency of the proposed technique in terms of accuracy and robustness.
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Cites work
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- Differential evolution -- a simple and efficient heuristic for global optimization over continuous spaces
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Cited in
(6)- Nonnegative mixed-norm convex optimization for mitotic cell detection in phase contrast microscopy
- Extraction of nucleolus candidate zone in white blood cells of peripheral blood smear images using curvelet transform
- Faster R-CNN with improved anchor box for cell recognition
- Detecting and tracking leukocytes in intravital video microscopy using a Hessian-based spatiotemporal approach
- Improved Otsu and Kapur approach for white blood cells segmentation based on LebTLBO optimization for the detection of leukemia
- Automatic detection and quantification of WBCs and RBCs using iterative structured circle detection algorithm
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