Analysis of Dynamics of a Biphasic Isothermal DNA Amplification Reaction

DOI10.1137/19M1268434MaRDI QIDQ5123488zbMATH OpenOpenAlexFDO

Authors Danielle Ciesielski, Stephanie McCalla, Tomáš Gedeon

Publication date 29 September 2020

Published in SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/19m1268434

zbMATH Keywords

DNA amplificationkinetic modelsystems biology

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cites work

• A constructive approach to quasi-steady state reductions
• An introduction to dynamical systems. Continuous and discrete
• Characteristic, completion or matching timescales? An analysis of temporary boundaries in enzyme kinetics
• Determining ``small parameters for quasi-steady state
• Nonlinear oscillations, dynamical systems, and bifurcations of vector fields
• Phase-plane geometries in coupled enzyme assays
• The quasi-steady-state approximations revisited: timescales, small parameters, singularities, and normal forms in enzyme kinetics
• The Quasi-Steady-State Assumption: A Case Study in Perturbation

Cited in

(1)

• In vitro DNA-based predator-prey system with oscillatory kinetics.

Describes a project that uses

Uses Software

• Mathematica

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