Andrews model

microbial growth model accounting for substrate inhibition

Also known as Haldane Model, Haldane-Andrews Model

deterministic model, dimensional model, mathematical model, nonlinear model, static model

Named after

Description

The Andrews model is a mathematical model that describes the specific growth rate of micoorganisms. It modifies the traditional Monod model to account for the negative effects of high substrate concentrations. When the substrate level becomes too high, the specific growth rate decreases due to inhibition. This model is widely used in fermentation and other bioprocesses to predict growth under inhibitory conditions.

Contained entity(-ies)

Andrews specific growth rate equation	$μ = \frac{μ_{m a x} c_{S}}{K_{M} + c_{S} + \frac{c_{S}^{2}}{K_{i}}}$
	$μ$ represents specific growth rate
	$μ_{m a x}$ represents maximum specific growth rate
	$c_{S}$ represents substrate concentration
	$K_{M}$ represents Monod constant
	$K_{i}$ represents inhibition constant (Andrews)

Computational task(s)

nonlinear parameter estimation (Andrews model)

Reference(s)

A mathematical model for the continuous culture of microorganisms utilizing inhibitory substrates	(invention)

Specialization(s)

Monod equation

Further link(s)

Item	Property
bacterial growth	modelled by

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