Assessing disease progression using a composite endpoint

DOI10.1177/0962280207070632MaRDI QIDQ5425025zbMATH OpenOpenAlexWikidataFDO

Authors Weng Kee Wong, Daniel E. Furst, Philip J. Clements, Jim B. Streisand

Publication date 7 November 2007

Published in Statistical Methods in Medical Research (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1177/0962280207070632

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Data-driven desirability function to measure patients’ disease progression in a longitudinal study
• Efficient analysis of time-to-event endpoints when the event involves a continuous variable crossing a threshold
• Consistency-adjusted alpha allocation methods for a time-to-event analysis of composite endpoints
• Efficient estimation of the distribution of time to composite endpoint when some endpoints are only partially observed
• An expected power approach for the assessment of composite endpoints and their components

Cites work

• Global Tests for Multiple Binary Outcomes
• scientific article; zbMATH DE number 5196542 (Why is no real title available?)
• Statistical Implications of the Choice between a Dichotomous or Continuous Trait in Studies of Interobserver Agreement

Cited in

(3)

• Desirability scores for assessing multiple outcomes in systemic rheumatic diseases
• An augmented approach to the desirability function
• Data-driven desirability function to measure patients’ disease progression in a longitudinal study

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