basksim
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Basksim
Description
Provides a unified syntax for the simulation-based comparison of different single-stage basket trial designs with a binary endpoint and equal sample sizes in all baskets. Methods include the designs by Baumann et al. (2025) <doi:10.1080/19466315.2024.2402275>, Schmitt and Baumann (2025) <doi:10.1080/19466315.2025.2486231>,Fujikawa et al. (2020) <doi:10.1002/bimj.201800404>,Berry et al. (2020) <doi:10.1177/1740774513497539>, andNeuenschwander et al. (2016) <doi:10.1002/pst.1730>. For the latter two designs, the functions are mostly wrappers for functions provided by the package 'bhmbasket'.
- A Basket Trial Design Based on Power Priors
- A Bayesian basket trial design that borrows information across strata based on the similarity between the posterior distributions of the response probability
- Bayesian hierarchical modeling of patient subpopulations: Efficient designs of Phase II oncology clinical trials
- Robust exchangeability designs for early phase clinical trials with multiple strata
- Systematic Comparison of Bayesian Basket Trial Designs with Unequal Sample Sizes and Proposal of a New Method Based on Power Priors
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