Bayesian multilayered mediation analysis for cancer pharmacogenomics

DOI10.1002/STA4.70020MaRDI QIDQ6963044zbMATH OpenFDO

Authors Dahun Seo, Veerabhadran Baladandayuthapani, Taesung Park, Min Jin Ha

Publication date 8 July 2025

Published in Stat (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1002/STA4.70020

zbMATH Keywords

drug sensitivityhigh-dimensional multilayered mediatorsinterventional effectsmultilayered Gaussian graphical modelsmultiomicsprobit model

Mathematics Subject Classification ID

Statistics (62-XX)

Cites work

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• Joint analysis of SNP and gene expression data in genetic association studies of complex diseases
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• Sparse principal component based high-dimensional mediation analysis

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