Border avoidance: necessary regularity for coefficients and viscosity approach

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Abstract: Motivated by the result of invariance of regular-boundary open sets in cite{CannarsaDaPratoFrankowska2009} and multi-stability issues in gene networks, our paper focuses on three closely related aims. First, we give a necessary local Lipschitz-like condition in order to expect invariance of open sets (for deterministic systems). Comments on optimality are provided via examples. Second, we provide a border avoidance (near-viability) counterpart of cite{CannarsaDaPratoFrankowska2009} for controlled Brownian diffusions and piecewise deterministic switched Markov processes (PDsMP). We equally discuss to which extent Lipschitz-continuity of the driving coefficients is needed. Finally, by applying the theoretical result on PDsMP to Hasty's model of bacteriophage (cite{hasty_pradines_dolnik_collins_00}, cite{crudu_debussche_radulescu_09}), we show the necessity of explicit modeling for the environmental cue triggering lysis.




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