Comparison of Two Smoothing Methods for Exploring Waning Vaccine Effects

DOI10.1111/1467-9876.00160MaRDI QIDQ4262930zbMATH OpenOpenAlexFDO

Authors L. Kathryn Durham, M. Elizabeth Halloran, Ira M. jun. Longini, Amita Manatunga

Publication date 3 July 2000

Published in Journal of the Royal Statistical Society Series C: Applied Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/1467-9876.00160

zbMATH Keywords

smoothingsurvival analysistime-dependent relative riskvaccine efficacy

Mathematics Subject Classification ID

Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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(8)

• Estimating Vaccine Efficacy Over Time After a Randomized Study is Unblinded
• A method for estimating time dependent intervention benefits under arbitrarily varying age and exogenous components of hazard
• Does Cox analysis of a randomized survival study yield a causal treatment effect?
• Allowing for two different mechanisms by which lesion free lung lobes occur in pigs after an experimental challenge: Vaccine performance comparisons
• Testing and Estimation of Time‐Varying Cause‐Specific Hazard Ratios with Covariate Adjustment
• Estimation of Waning Vaccine Efficacy
• The Two-Way Proportional Hazards Model
• Improved estimation of the cumulative incidence of rare outcomes

Describes a project that uses

Uses Software

• Matlab

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