Data for LSA analysis

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This code is supplementary to the paper Kinetic modulation of bacterial hydrolases by microbial community structure in coastal waters by Abad et al. It contains the following files: 0) README.txt: This README file. 1) Complex saturation kinetics modelling.R: It contains the code developed for the determination of the kinetic parameters of the extracellular enzymatic activities by fitting thehydrolysis rates to four different kinetic models of increasing complexity using a non-linear least squares regression. 2) LSA functions.R: It contains the functions implemented in R to perform the Local Similarity analysis. Our specific modifications related to the function LocalSimilarity3 are indicated by the comment #New: modified function. 3) LSA script.R: It is an updated version of the code developed by Ruan et al (2006) that has been used to perform the Local Similarity analysis in our study. The comment #New: modified function indicates our specific modifications within the original code. The following modifications were added to the original code: The calculation of the linear interpolation of missing values (NAs) using the R package zoo (Zeleis et al 2021). The calculation of the q-values by using the R package qvalue (Storey et al 2022). NOTE: it is important to set the working directory in the same folder where all the provided files are stored.











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