Phenotypic, genetic, and epigenetic data from 29 Serratia marcescens strains from an evolution experiment
DOI10.5281/zenodo.5396905Zenodo5396905MaRDI QIDQ6675768FDOQ6675768
Dataset published at Zenodo repository.
Tarmo Ketola, Roghaieh Ashrafi, Matthieu Bruneaux, Ilkka Kronholm
Publication date: 2 September 2021
This dataset contains phenotypic, genetic, and epigenetic data from 29 Serratia marcescens strains from an evolution experiment. In a previous study (https://doi.org/10.1111/evo.12148), the bacterium S. marcescens was left to evolve from a common ancestor culture in replicated populations kept under different temperature regimes, and evolved clones were isolated and their phenotypes measured. Here, we randomly selected 28 evolved clones from this experiment, as well as the original reference strain, and used PacBio single molecule real-time (SMRT) sequencing to obtain genetic and epigenetic (N6-methyladenine modifications, m6A) data. The goal of our study was to obtain a detailed description of the methylation landscape of S. marcescens and to examine the potential contributions of genetic and epigenetic changes to phenotypic adaptation.
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